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A dendritic spine (or spine) is a small membrane protrusion from a neuron's dendrite that typically receives input from a single axon at the synapse.Dendritic spines serve as a storage site for synaptic strength and help transmit electrical signals to the neuron's cell body.
There are many recognized spinal diseases, some more common than others. Spinal disease also includes cervical spine diseases, which are diseases in the vertebrae of the neck. A lot of flexibility exists within the cervical spine and because of that, it is common for an individual to damage that area, especially over a long period of time.
However, dendritic filopodia can take on spine-like morphologies even without post-synaptic density proteins, pointing to actin remodeling as the primary process responsible for the development of spines from filopodia. Cytoskeletal analyses of spines versus filopodia have found that a spine-like morphology is associated with higher numbers of ...
An apical dendrite is a dendrite that emerges from the apex of a pyramidal cell. [1] Apical dendrites are one of two primary categories of dendrites, and they distinguish the pyramidal cells from spiny stellate cells in the cortices.
The spine apparatus’ ability to release calcium into the cytosol is thought to contribute to the development of synaptic plasticity. This was first shown in an experiment using synaptopodin(SP)-deficient mice, which do not show a spine apparatus in dendritic spines. [8] These SP-deficient mice showed a decrease in long-term potentiation (LTP ...
The disease is an international health problem, as C. tetani endospores are ubiquitous. Endospores can be introduced into the body through a puncture wound ( penetrating trauma ). Due to C. tetani being an anaerobic bacterium, it and its endospores thrive in environments that lack oxygen , such as a puncture wound.
Blastic plasmacytoid dendritic cell neoplasm typically responds to chemotherapy regimens used to treat hematological malignancies. All too often, however, the disease rapidly recurs and does so in a more drug-resistant form. [5] Furthermore, the disease may occur in association with the myelodysplastic syndrome or transform to acute myeloid ...
In a simulated disease state where axons were destroyed, some neurons formed dendrodendritic synapses to compensate. [8] In experiments where deafferentation or axotomy was performed in the lateral geniculate nucleus (LGN) of cats it was found that pre-synaptic dendrites began to form to compensate for the lost axons. [ 8 ]