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  2. Protein pKa calculations - Wikipedia

    en.wikipedia.org/wiki/Protein_pKa_calculations

    The pK a values of an amino acid side chain in solution is typically inferred from the pK a values of model compounds (compounds that are similar to the side chains of amino acids). See Amino acid for the pK a values of all amino acid side chains inferred in such a way. There are also numerous experimental studies that have yielded such values ...

  3. Zwitterion - Wikipedia

    en.wikipedia.org/wiki/Zwitterion

    Theoretical calculations have been used to show that zwitterions may also be present in the gas phase for some cases different from the simple carboxylic acid-to-amine transfer. [6] The pK a values for deprotonation of the common amino acids span the approximate range 2.15 ± 0.2. This is also consistent with the zwitterion being the ...

  4. Acid dissociation constant - Wikipedia

    en.wikipedia.org/wiki/Acid_dissociation_constant

    In particular, the pH of a solution can be predicted when the analytical concentration and pK a values of all acids and bases are known; conversely, it is possible to calculate the equilibrium concentration of the acids and bases in solution when the pH is known. These calculations find application in many different areas of chemistry, biology ...

  5. Histidine - Wikipedia

    en.wikipedia.org/wiki/Histidine

    Histidine ball and stick model spinning. Histidine (symbol His or H) [2] is an essential amino acid that is used in the biosynthesis of proteins.It contains an α-amino group (which is in the protonated –NH 3 + form under biological conditions), a carboxylic acid group (which is in the deprotonated –COO − form under biological conditions), and an imidazole side chain (which is partially ...

  6. Glycine - Wikipedia

    en.wikipedia.org/wiki/Glycine

    Glycine (symbol Gly or G; [6] / ˈ ɡ l aɪ s iː n / ⓘ) [7] is an amino acid that has a single hydrogen atom as its side chain. It is the simplest stable amino acid. Glycine is one of the proteinogenic amino acids. It is encoded by all the codons starting with GG (GGU, GGC, GGA, GGG). [8]

  7. Threonine - Wikipedia

    en.wikipedia.org/wiki/Threonine

    Threonine (symbol Thr or T) [2] is an amino acid that is used in the biosynthesis of proteins.It contains an α-amino group (which is in the protonated −NH + 3 form when dissolved in water), a carboxyl group (which is in the deprotonated −COO − form when dissolved in water), and a side chain containing a hydroxyl group, making it a polar, uncharged amino acid.

  8. Bicine - Wikipedia

    en.wikipedia.org/wiki/Bicine

    It is one of Good's buffers and has a pKa of 8.35 at 20 °C. [1] It is prepared by the reaction of glycine with ethylene oxide, followed by hydrolysis of the resultant lactone. [2] Bicine is a contaminant in amine systems used for gas sweetening. It is formed by amine degradation in the presence of O 2, SO 2, H 2 S or Thiosulfate. [3]

  9. Asparagine - Wikipedia

    en.wikipedia.org/wiki/Asparagine

    Asparagine (symbol Asn or N [2]) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH + 3 form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO − form under biological conditions), and a side chain carboxamide ...