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A neuronal lineage marker is an endogenous tag that is expressed in different cells along neurogenesis and differentiated cells such as neurons. It allows detection and identification of cells by using different techniques. A neuronal lineage marker can be either DNA, mRNA or RNA expressed in a cell of interest.
Nestin, a protein marker for neural stem cells, is also expressed in follicle stem cells and their immediate, differentiated progeny. The hair follicle bulge area is an abundant, easily accessible source of actively growing pluripotent adult stem cells.
The most widely accepted model of an adult NSC is a radial, glial fibrillary acidic protein-positive cell. Quiescent stem cells are Type B that are able to remain in the quiescent state due to the renewable tissue provided by the specific niches composed of blood vessels, astrocytes, microglia , ependymal cells, and extracellular matrix present ...
22152 Ensembl ENSG00000258947 ENSMUSG00000062380 UniProt Q13509 Q9ERD7 RefSeq (mRNA) NM_006086 NM_001197181 NM_023279 RefSeq (protein) NP_001184110 NP_006077 NP_075768 Location (UCSC) Chr 16: 89.92 – 89.94 Mb Chr 8: 124.14 – 124.15 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Tubulin beta-3 chain, Class III β-tubulin, βIII-tubulin (β3-tubulin) or β-tubulin III, is a ...
The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts.
Glial fibrillary acidic protein (GFAP) is a protein that is encoded by the GFAP gene in humans. [5] It is a type III intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS), including astrocytes [6] and ependymal cells during development. [7]
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Human subventricular zone. From a paper by Oscar Arias-Carrión, 2008 In an embryonic rat brain, GAD67-binding marker tends to concentrate in subventricular zone.An image from Popp et al., 2009.