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  2. Blood sugar level - Wikipedia

    en.wikipedia.org/wiki/Blood_sugar_level

    The blood sugar level, blood sugar concentration, blood glucose level, or glycemia is the measure of glucose concentrated in the blood. The body tightly regulates blood glucose levels as a part of metabolic homeostasis .

  3. Blood sugar regulation - Wikipedia

    en.wikipedia.org/wiki/Blood_sugar_regulation

    Blood sugar regulation is the process by which the levels of blood sugar, the common name for glucose dissolved in blood plasma, are maintained by the body within a narrow range. The regulation of glucose levels through Homeostasis. This tight regulation is referred to as glucose homeostasis. Insulin, which lowers blood sugar, and glucagon ...

  4. Homeostasis - Wikipedia

    en.wikipedia.org/wiki/Homeostasis

    In response to a lowering of the plasma sodium concentration, or to a fall in the arterial blood pressure, the juxtaglomerular cells release renin into the blood. [ 64 ] [ 65 ] [ 66 ] Renin is an enzyme which cleaves a decapeptide (a short protein chain, 10 amino acids long) from a plasma α-2-globulin called angiotensinogen .

  5. Insulin receptor - Wikipedia

    en.wikipedia.org/wiki/Insulin_receptor

    The insulin receptor (IR) is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of receptor tyrosine kinase. [5] Metabolically, the insulin receptor plays a key role in the regulation of glucose homeostasis; a functional process that under degenerate conditions may result in a range of clinical manifestations including diabetes and cancer.

  6. Insulin - Wikipedia

    en.wikipedia.org/wiki/Insulin

    Glucagon increases blood glucose by stimulating glycogenolysis and gluconeogenesis in the liver. [8] [10] The secretion of insulin and glucagon into the blood in response to the blood glucose concentration is the primary mechanism of glucose homeostasis. [10]

  7. Insulin signal transduction pathway - Wikipedia

    en.wikipedia.org/wiki/Insulin_signal...

    The insulin transduction pathway is a biochemical pathway by which insulin increases the uptake of glucose into fat and muscle cells and reduces the synthesis of glucose in the liver and hence is involved in maintaining glucose homeostasis. This pathway is also influenced by fed versus fasting states, stress levels, and a variety of other hormones.

  8. Glucose - Wikipedia

    en.wikipedia.org/wiki/Glucose

    As a result of its importance in human health, glucose is an analyte in glucose tests that are common medical blood tests. [121] Eating or fasting prior to taking a blood sample has an effect on analyses for glucose in the blood; a high fasting glucose blood sugar level may be a sign of prediabetes or diabetes mellitus. [122]

  9. Beta cell - Wikipedia

    en.wikipedia.org/wiki/Beta_cell

    Beta cells (β-cells) are specialized endocrine cells located within the pancreatic islets of Langerhans responsible for the production and release of insulin and amylin. [1] Constituting ~50–70% of cells in human islets, beta cells play a vital role in maintaining blood glucose levels. [2] Problems with beta cells can lead to disorders such ...

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