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Renal cell carcinoma (RCC) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport primary urine. RCC is the most common type of kidney cancer in adults, responsible for approximately 90–95% of cases. [1] It is more common in men (with a male-to-female ...
Kidney cancer; Other names: Renal cancer: Micrograph showing the most common type of kidney cancer (clear cell renal cell carcinoma). H&E stain. Specialty: Oncology nephrology Urology: Symptoms: Blood in the urine, lump in the abdomen, back pain [1] [2] [3] Usual onset: After the age of 45 [4] Types: Renal cell carcinoma (RCC), transitional ...
Papillary renal cell carcinoma (PRCC) is a malignant, heterogeneous tumor originating from renal tubular epithelial cells of the kidney, which comprises approximately 10-15% of all kidney neoplasms. [ 1 ] Based on its morphological features, PRCC can be classified into two main subtypes, which are type 1 (basophilic) and type 2 (eosinophilic).
Generally, the cells have a clear cytoplasm, are surrounded by a distinct cell membrane and contain round and uniform nuclei. [citation needed] Microscopically, CCRCCs are graded by the ISUP/WHO as follows: [1][2] Grade 1: Inconspicuous and basophilic nucleoli at magnification of 400 times. Grade 2: Clearly visible and eosinophilic nucleoli at ...
Renal medullary carcinoma is a rare type of cancer that affects the kidney.It tends to be aggressive, difficult to treat, and is often metastatic at the time of diagnosis. . Most individuals with this type of cancer have sickle cell trait or rarely sickle cell disease, suggesting that the sickle cell trait may be a risk factor for this type of ca
Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) or Reed's syndrome is rare autosomal dominant disorder associated with benign smooth muscle tumors and an increased risk of renal cell carcinoma. It is characterised by multiple cutaneous leiomyomas and, in women, uterine leiomyomas. It predisposes individuals to renal cell cancer, an ...
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