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Dehydroepiandrosterone (DHEA) is a steroid hormone produced in the adrenal cortex from cholesterol. [5] It is the primary precursor of both the androgen and estrogen sex hormones. DHEA is also called dehydroisoandrosterone or dehydroandrosterone. Androstenedione (A4) is an androgenic steroid produced by the testes, adrenal cortex, and ovaries.
Testosterone is also synthesized in far smaller total quantities in women by the adrenal glands, thecal cells of the ovaries, and, during pregnancy, by the placenta. [158] In the testes, testosterone is produced by the Leydig cells. [159] The male generative glands also contain Sertoli cells, which require testosterone for spermatogenesis.
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. [1][2] They are found above the kidneys. Each gland has an outer cortex which produces steroid hormones and an inner medulla.
Anatomical terminology. [edit on Wikidata] The endocrine system[1] is a messenger system in an organism comprising feedback loops of hormones that are released by internal glands directly into the circulatory system and that target and regulate distant organs. In vertebrates, the hypothalamus is the neural control center for all endocrine systems.
15632. Anatomical terminology. [edit on Wikidata] The adrenal cortex is the outer region and also the largest part of the adrenal gland. It is divided into three separate zones: zona glomerulosa, zona fasciculata and zona reticularis. Each zone is responsible for producing specific hormones. It is also a secondary site of androgen synthesis.
Only certain organs in the body, such as the gonads and the adrenal glands, produce the androgen testosterone. Testosterone is converted into dihydrotestosterone, a chemically similar androgen, in cells containing the enzyme 5-alpha reductase. Both androgens exert their influence through binding with the androgen receptor.
In premenopausal women, the adrenal glands and ovaries each produce about half of the total androstenedione (about 3 mg/day). After menopause, androstenedione production is about halved, due primarily to the reduction of the steroid secreted by the ovary. Nevertheless, androstenedione is the principal steroid produced by the postmenopausal ovary.
Sex hormone. Sex hormones, also known as sex steroids, gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate steroid hormone receptors. [1] The sex hormones include the androgens, estrogens, and progestogens. Their effects are mediated by slow genomic mechanisms through nuclear receptors as well as by fast ...