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  2. Erythrocyte sedimentation rate - Wikipedia

    en.wikipedia.org/wiki/Erythrocyte_sedimentation_rate

    The ESR is decreased in polycythemia, hyperviscosity, sickle cell anemia, leukemia, chronic fatigue syndrome, [4] low plasma protein (due to liver or kidney disease) and congestive heart failure. Although increases in immunoglobulins usually increase the ESR, very high levels can reduce it again due to hyperviscosity of the plasma. [ 5 ]

  3. Macrophage activation syndrome - Wikipedia

    en.wikipedia.org/wiki/Macrophage_activation_syndrome

    Despite marked systemic inflammation, the erythrocyte sedimentation rate (ESR) is paradoxically depressed, caused by low fibrinogen levels. The low ESR helps to distinguish the disorder from a flare of the underlying rheumatic disorder, in which case the ESR is usually elevated. A bone marrow biopsy or aspirate usually shows hemophagocytosis.

  4. Elevated alkaline phosphatase - Wikipedia

    en.wikipedia.org/wiki/Elevated_alkaline_phosphatase

    Elevated levels are also associated with diabetes, hypertension, and cardiovascular disease; it was found that elevated levels are associated with elevated serum C-reactive protein (CRP), which could reflect an inflammatory and atherogenic milieu, possibly an alternative cause for elevated serum alkaline phosphatase. [10] Chronic kidney disease ...

  5. C-reactive protein - Wikipedia

    en.wikipedia.org/wiki/C-reactive_protein

    C-reactive protein (CRP) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells .

  6. Vasculitis - Wikipedia

    en.wikipedia.org/wiki/Vasculitis

    Their results will generally show signs of inflammation in the body, such as increased erythrocyte sedimentation rate (ESR), elevated C-reactive protein (CRP), anemia, increased white blood cell count and eosinophilia. Other possible findings are elevated antineutrophil cytoplasmic antibody (ANCA) levels and hematuria.

  7. Rheumatoid arthritis - Wikipedia

    en.wikipedia.org/wiki/Rheumatoid_arthritis

    Low-positive RF or low-positive ACPA gives 2 points; High-positive RF or high-positive ACPA gives 3 points; acute phase reactants: 1 point for elevated erythrocyte sedimentation rate, ESR, or elevated CRP value (c-reactive protein) duration of arthritis: 1 point for symptoms lasting six weeks or longer

  8. Polymyalgia rheumatica - Wikipedia

    en.wikipedia.org/wiki/Polymyalgia_rheumatica

    Many conditions can cause an elevated ESR, so this test alone is not proof that a person has polymyalgia rheumatica. [17] [18] Another test that checks the level of C-reactive protein (CRP) in the blood may also be conducted. CRP is produced by the liver in response to an injury or infection, and people with polymyalgia rheumatica usually have ...

  9. Ulcerative colitis - Wikipedia

    en.wikipedia.org/wiki/Ulcerative_colitis

    UC may cause high levels of inflammation throughout the body, which may be quantified with serum inflammatory markers, such as CRP and ESR. However, elevated inflammatory markers are not specific for UC and elevations are commonly seen in other conditions, including infection.