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Methylpyridinium is prepared by treating pyridine with dimethylsulfate: [2]. C 5 H 5 N + (CH 3 O) 2 SO 2 → [C 5 H 5 NCH 3] + CH 3 OSO − 3. It is found in some coffee products. [3] It is not present in unroasted coffee beans, but is formed during roasting from its precursor chemical, trigonelline. [3]
Methylphenethylamines have a phenethylamine backbone and a methyl group attached at one of these points. Methylphenethylamine may refer to: α-Methylphenethylamine (amphetamine) β-Methylphenethylamine; N-Methylphenethylamine (an endogenous trace amine in humans) 2-Methylphenethylamine; 3-Methylphenethylamine; 4-Methylphenethylamine
RSO 2 Cl + R' 2 NH → RSO 2 NR' 2 + HCl. A base such as pyridine is typically added to absorb the HCl that is generated. Illustrative is the synthesis of sulfonylmethylamide. [3] The reaction of primary and secondary amines with benzenesulfonyl chloride is the basis of the Hinsberg reaction, a method for detecting primary and secondary amines.
2-Methylpyridine, or 2-picoline, is the compound described with formula C 6 H 7 N. 2-Picoline is a colorless liquid that has an unpleasant odor similar to pyridine. It is mainly used to make vinylpyridine and the agrichemical nitrapyrin .
2-Methylphenethylamine (2MPEA) is an organic compound with the chemical formula of C 9 H 13 N. 2MPEA is a human trace amine associated receptor 1 (TAAR1) agonist, [3] a property which it shares with its monomethylated phenethylamine isomers, such as amphetamine (α-methylphenethylamine), β-methylphenethylamine, and N-methylphenethylamine (a trace amine).
The structures of pyridine and pyridinium are almost identical. [87] The pyridinium cation is isoelectronic with benzene. Pyridinium p-toluenesulfonate (PPTS) is an illustrative pyridinium salt; it is produced by treating pyridine with p-toluenesulfonic acid. In addition to protonation, pyridine undergoes N-centred alkylation, acylation, and N ...
Phenethylamine is a primary amine, the amino-group being attached to a benzene ring through a two-carbon, or ethyl group. [10] It is a colourless liquid at room temperature that has a fishy odor, and is soluble in water, ethanol and ether. [10] Its density is 0.964 g/ml and its boiling point is 195 °C. [10]
MPP + (1-methyl-4-phenylpyridinium) is a positively charged organic molecule with the chemical formula C 12 H 12 N +. It is a monoaminergic neurotoxin that acts by interfering with oxidative phosphorylation in mitochondria by inhibiting complex I , leading to the depletion of ATP and eventual cell death .