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Once these solvents or gases are inhaled, the extensive capillary surface of the lungs rapidly absorbs the solvent or gas, and blood levels peak rapidly. The intoxication effects occur so quickly that the effects of inhalation can resemble the intensity of effects produced by intravenous injection of other psychoactive drugs.
Low viscosity of an ingested hydrocarbon is considered a major factor promoting aspiration (presumably for mechanical reasons). Contrary to aspiration hydrocarbon pneumonitis, hydrocarbon (solvent) vapor inhalation manifests primarily in either central nervous system or cardiac effects. [1]
Chronic solvent-induced encephalopathy (CSE) is a condition induced by long-term exposure to organic solvents, often—but not always—in the workplace, that lead to a wide variety of persisting sensorimotor polyneuropathies and neurobehavioral deficits even after solvent exposure has been removed.
Its high volatility makes it an inhalation hazard. [ 26 ] [ 27 ] It can also be absorbed through the skin. [ 1 ] [ 28 ] Symptoms of acute overexposure to dichloromethane via inhalation include difficulty concentrating, dizziness , fatigue , nausea , headaches , numbness, weakness, and irritation of the upper respiratory tract and eyes .
The term "amyl nitrite" encompasses several isomers.In older literature, the common non-systematic name amyl was often used for the pentyl group, where the amyl group is a linear or normal (n) alkyl group, and the resulting amyl nitrite would have the structural formula CH 3 (CH 2) 3 CH 2 ONO, also referred to as n-amyl nitrite.
An example of an ether is the solvent diethyl ether. [1] Halogenated ethers differ from other ethers because there are one or more halogen atoms—fluorine, chlorine, bromine, or iodine—as substituents on the carbon groups. . [2] Examples of commonly used halogenated ethers include isoflurane, sevofluorane and desflurane. [3]
Despite Davy's discovery that inhalation of nitrous oxide could relieve a conscious person from pain, another 44 years elapsed before doctors attempted to use it for anaesthesia. The use of nitrous oxide as a recreational drug at "laughing gas parties", primarily arranged for the British upper class, became an immediate success beginning in ...
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