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Tentative evidence does not support the use of bisphosphonates as a standard treatment for secondary osteoporosis in children. [168] Different bisphosphonates have not been directly compared, therefore it is unknown if one is better than another. [122] Fracture risk reduction is between 25 and 70% depending on the bone involved. [122]
Bisphosphonates are a class of drugs that prevent the loss of bone density, used to treat osteoporosis and similar diseases. They are the most commonly prescribed drugs used to treat osteoporosis. [1] They are called bisphosphonates because they have two phosphonate (PO(OH) 2) groups. They are thus also called diphosphonates (bis-or di ...
The Agency recommended that doctors who prescribe bisphosphonate-containing medicines should be aware that atypical fractures may occur rarely in the femur, especially after long-term use, and that doctors who are prescribing these medicines for the prevention or treatment of osteoporosis should regularly review the need for continued treatment ...
The two main types of anti-resorptive drugs are bisphosphonate and denosumab. These drugs help to decrease the risk of bone fracture and bone pain. Because the mandible has a faster remodeling rate compared to other bones in the body, it is more affected by the effects of these drugs. [30] Bisphosphonate. Bisphosphonates are either administered ...
These medications also provide symptomatic relief to common arthritic joint symptoms including swelling, tenderness, pain, stiffness, and decreased range of motion. [7] These symptoms may persist or occur periodically and if symptoms are not managed, major complications may develop including permanent joint changes, chronic pain, and functional ...
Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. [4] It is taken by mouth. [ 4 ] Use is often recommended together with vitamin D , calcium supplementation , and lifestyle changes.
Ibandronic acid is a bisphosphonate medication used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. [4] It may also be used to treat hypercalcemia (elevated blood calcium levels). It is typically formulated as its sodium salt ibandronate sodium. [medical citation needed]
The pain medication paracetamol (acetaminophen) is the first line treatment for osteoarthritis. [ 61 ] [ 94 ] Pain relief does not differ according to dosage. [ 62 ] However, a 2015 review found acetaminophen to have only a small short-term benefit with some concerns on abnormal results for liver function test . [ 95 ]
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