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  2. Blood-oxygenation-level–dependent imaging - Wikipedia

    en.wikipedia.org/wiki/Blood-oxygenation-level...

    The proof of concept of BOLD-contrast imaging was provided by Seiji Ogawa and Colleagues in 1990, following an experiment which demonstrated that an in vivo change of blood oxygenation could be detected with MRI. [6] In Ogawa's experiments, blood-oxygenation-level–dependent imaging of rodent brain slice contrast in different components of the ...

  3. Signal enhancement by extravascular water protons - Wikipedia

    en.wikipedia.org/wiki/Signal_enhancement_by...

    Signal enhancement by extravascular water protons, or SEEP, is a contrast mechanism for functional magnetic resonance imaging (fMRI), which is an alternative to the more commonly employed BOLD (blood-oxygen-level dependent) contrast. This mechanism for image contrast changes corresponding to changes in neuronal activity was first proposed by Dr ...

  4. Functional magnetic resonance imaging - Wikipedia

    en.wikipedia.org/wiki/Functional_magnetic...

    The primary form of fMRI uses the blood-oxygen-level dependent (BOLD) contrast, [4] discovered by Seiji Ogawa in 1990. This is a type of specialized brain and body scan used to map neural activity in the brain or spinal cord of humans or other animals by imaging the change in blood flow ( hemodynamic response ) related to energy use by brain ...

  5. Stages of human death - Wikipedia

    en.wikipedia.org/wiki/Stages_of_human_death

    The aforementioned mechanism is the most common cause of brain death; however, this increase in intracranial pressure does not always occur due to an arrest in cardiopulmonary function. [5] Traumatic brain injuries and subarachnoid hemorrhages can also increase the intracranial pressure in the brain leading to a cessation of brain function and ...

  6. Thanatology - Wikipedia

    en.wikipedia.org/wiki/Thanatology

    Thanatology is the scientific study of death and the losses brought about as a result. It investigates the mechanisms and forensic aspects of death, such as bodily changes that accompany death and the postmortem period, as well as wider psychological and social aspects related to death. It is primarily an interdisciplinary study offered as a ...

  7. Coagulative necrosis - Wikipedia

    en.wikipedia.org/wiki/Coagulative_necrosis

    Coagulative necrosis is a type of accidental cell death typically caused by ischemia or infarction. In coagulative necrosis, the architectures of dead tissue are preserved for at least a couple of days. [1] It is believed that the injury denatures structural proteins as well as lysosomal enzymes, thus blocking the proteolysis of the damaged cells.

  8. LSD - Wikipedia

    en.wikipedia.org/wiki/LSD

    In contrast to schizophrenia, LSD can induce transcendent experiences, or mental states that transcend the experience of everyday consciousness, with lasting psychological benefit. [ 12 ] [ 157 ] During this time, the Central Intelligence Agency (CIA) began using LSD in the research project Project MKUltra , which used psychoactive substances ...

  9. Algor mortis - Wikipedia

    en.wikipedia.org/wiki/Algor_mortis

    A measured rectal temperature can give some indication of the time of death. Although the heat conduction which leads to body cooling follows an exponential decay curve, it can be approximated as a linear process: 2 °C during the first hour and 1 °C per hour until the body nears ambient temperature.