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Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. [1] Tentative evidence has found other antibiotics to be more effective, and therefore it is no longer generally recommended for second-degree (partial-thickness) burns, but is still ...
Silver sulfadiazine (SSD) is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. [4] [21] It was discovered in the 1960s, [22] and was the standard topical antimicrobial for burn wounds for decades. [23] [24]
It is a second-line treatment for otitis media, prophylaxis of rheumatic fever, chancroid, chlamydia, and infections by Haemophilus influenzae. [1] It is also used as adjunct therapy for chloroquine-resistant malaria and several forms of bacterial meningitis. [4] It is taken by mouth. [1] Sulfadiazine is available in multiple generic tablets of ...
[68] [69] Silver sulfadiazine (a type of antibiotic) is not recommended as it potentially prolongs healing time. [67] [70] There is insufficient evidence to support the use of dressings containing silver [71] or negative-pressure wound therapy. [72] Silver sulfadiazine does not appear to differ from silver containing foam dressings with respect ...
Imiquimod is a patient-applied cream prescribed to treat genital warts, Bowens disease (squamous cell carcinoma in situ), and, secondary to surgery, for basal cell carcinoma, [7] [8] as well as actinic keratosis. [9] Imiquimod 5% cream is indicated for the topical treatment of: external genital and perianal warts (condylomata acuminata) in ...
Sulfathiazole is an organosulfur compound used as a short-acting sulfa drug. [1] Formerly, it was a common oral and topical antimicrobial, until less toxic alternatives were discovered. [2] Sulfathiazole exists in various forms . The imine tautomer is dominant in solid samples. [3]
It is approved in the United States as a treatment and preventive measure against malaria. [6] The combination is considered to be more effective in treating malaria caused by Plasmodium falciparum than that caused by P. vivax, for which chloroquine is considered more effective, though in the absence of a species-specific diagnosis, the sulfadoxine-pyrimethamine combination may be indicated. [7]
The plasma concentration reached a steady state on Day 5 of repeated administration study when nadifloxacin 1% cream was applied at 5 g twice daily to normal healthy individuals for a period of 7 days. The plasma concentration reached a peak of 4.1 ng/ml at 8 hours post-final dosing with an elimination half-life of 23.2 hours.
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