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  2. Acute exacerbation of chronic obstructive pulmonary disease

    en.wikipedia.org/wiki/Acute_exacerbation_of...

    The definition of a COPD exacerbation is commonly described as "lost in translation", [9] meaning that there is no universally accepted standard with regard to defining an acute exacerbation of COPD. Many organizations consider it a priority to create such a standard, as it would be a major step forward in the diagnosis and quality of treatment ...

  3. Chronic obstructive pulmonary disease - Wikipedia

    en.wikipedia.org/wiki/Chronic_obstructive...

    Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...

  4. Erdosteine - Wikipedia

    en.wikipedia.org/wiki/Erdosteine

    The RESTORE study (Reducing Exacerbations and Symptoms by Treatment with ORal Erdosteine in COPD) was a multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of erdosteine 300 mg/bid added to usual maintenance therapy vs. placebo over 12-months, a period long enough to avoid bias due to seasonal ...

  5. Lower respiratory tract infection - Wikipedia

    en.wikipedia.org/wiki/Lower_respiratory_tract...

    [13] [15] Pneumonia is also the leading cause of death in children less than five years of age in low income countries. [15] The most common cause of pneumonia is pneumococcal bacteria, Streptococcus pneumoniae accounts for 2/3 of bacteremic pneumonias. [16] Invasive pneumococcal pneumonia has a mortality rate of around 20%. [14]

  6. Obstructive lung disease - Wikipedia

    en.wikipedia.org/wiki/Obstructive_lung_disease

    COPD is defined as a forced expiratory volume in 1 second divided by the forced vital capacity (FEV1/FVC) that is less than 0.7 (or 70%). [8] The residual volume, the volume of air left in the lungs following full expiration, is often increased in COPD, as is the total lung capacity, while the vital capacity remains relatively normal.

  7. Moxifloxacin - Wikipedia

    en.wikipedia.org/wiki/Moxifloxacin

    The European Medicines Agency has advised that, for pneumonia, acute bacterial sinusitis, and acute exacerbations of COPD, it should only be used when other antibiotics are inappropriate. [20] [21] Oral and intravenous moxifloxacin have not been approved for children.

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