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  2. Homeostatic model assessment - Wikipedia

    en.wikipedia.org/wiki/Homeostatic_model_assessment

    IR is insulin resistance and %β is the β-cell function (more precisely, an index for glucose tolerance, i.e. a measure for the ability to counteract the glucose load). Insulin is given in μU/mL. [7] Glucose and insulin are both during fasting. [2] This model correlated well with estimates using the euglycemic clamp method (r = 0.88). [2]

  3. Intensive insulin therapy - Wikipedia

    en.wikipedia.org/wiki/Intensive_insulin_therapy

    This meal-associated (prandial) insulin production is roughly proportional to the amount of carbohydrate in the meal. Intensive or flexible therapy involves supplying a continual supply of insulin to serve as the basal insulin, supplying meal insulin in doses proportional to nutritional load of the meals, and supplying extra insulin when needed ...

  4. Insulin (medication) - Wikipedia

    en.wikipedia.org/wiki/Insulin_(medication)

    Prandial insulin, also called mealtime or bolus insulin, is designed as a bolus dose of insulin prior to a meal to regulate the spike in blood glucose that occurs following a meal. The dose of prandial insulin may be static, or may be calculated by the patient using either their current blood sugar, planned carbohydrate intake, or both.

  5. Glucose clamp technique - Wikipedia

    en.wikipedia.org/wiki/Glucose_clamp_technique

    The hyperglycemic clamps are often used to assess insulin secretion capacity. Hyperinsulinemic-euglycemic clamp technique: The plasma insulin concentration is acutely raised and maintained at 100 μU/ml by a continuous infusion of insulin. Meanwhile, the plasma glucose concentration is held constant at basal levels by a variable glucose infusion.

  6. Conventional insulin therapy - Wikipedia

    en.wikipedia.org/wiki/Conventional_insulin_therapy

    Conventional insulin therapy is characterized by: Insulin injections of a mixture of regular (or rapid) and intermediate acting insulin are performed two times a day, or to improve overnight glucose, mixed in the morning to cover breakfast and lunch, but with regular (or rapid) acting insulin alone for dinner and intermediate acting insulin at bedtime (instead of being mixed in at dinner).

  7. Diabetes management - Wikipedia

    en.wikipedia.org/wiki/Diabetes_management

    Insulin is usually taken several times per day in patients who require it to control their diabetes. [32] Often patients usually take long acting insulin once a day and then take insulin before meals. The time of onset of the insulin determines how far in advance patients should take the insulin before they eat. [32]

  8. Insulin index - Wikipedia

    en.wikipedia.org/wiki/Insulin_index

    The insulin index of food represents how much it elevates the concentration of insulin in the blood during the two-hour period after the food is ingested. The index is similar to the glycemic index (GI) and glycemic load (GL), but rather than relying on blood glucose levels, the Insulin Index is based upon blood insulin levels.

  9. Disposition index - Wikipedia

    en.wikipedia.org/wiki/Disposition_index

    The Disposition index (DI) is a measure for the loop gain of the insulin-glucose feedback control system. It is defined as the product of insulin sensitivity times the amount of insulin secreted in response to blood glucose levels.

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