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  2. CRISPR - Wikipedia

    en.wikipedia.org/wiki/CRISPR

    Cas9 (or "CRISPR-associated protein 9") is an enzyme that uses CRISPR sequences as a guide to recognize and open up specific strands of DNA that are complementary to the CRISPR sequence. Cas9 enzymes together with CRISPR sequences form the basis of a technology known as CRISPR-Cas9 that can be used to edit genes within living organisms.

  3. Engineer explains how Nobel Prize-winning CRISPR ... - AOL

    www.aol.com/news/engineer-explains-nobel-prize...

    Researchers have been able to manipulate large chunks of genetic code for almost 50 years. This newfound ability is called gene-editing, the tool is called CRISPR, and it’s being used worldwide ...

  4. 2 Biotech Stocks That Are Screaming Buys This Month - AOL

    www.aol.com/2-biotech-stocks-screaming-buys...

    CRISPR's shares are down by 27% year to date, and Moderna's are down by 41%. Regardless of their performances so far in 2024, both stocks are worth investing in this month. Read on to find out why. 1.

  5. FDA approves cure for sickle cell disease, the first ... - AOL

    www.aol.com/news/fda-approves-cure-sickle-cell...

    To do so, chemotherapy is used to destroy the patient’s bone marrow. Only then can the edited stem cells be reinfused into the patient, followed by another month or two in the hospital to allow ...

  6. Victoria Gray - Wikipedia

    en.wikipedia.org/wiki/Victoria_Gray

    Victoria Gray was the first patient ever to be treated with the gene-editing tool CRISPR for sickle-cell disease. [1]This marked the initial indication that a cure is attainable for individuals born with sickle-cell disease and another severe blood disorder, beta-thalassemia.

  7. Off-target genome editing - Wikipedia

    en.wikipedia.org/wiki/Off-target_genome_editing

    Off-target genome editing refers to nonspecific and unintended genetic modifications that can arise through the use of engineered nuclease technologies such as: clustered, regularly interspaced, short palindromic repeats ()-Cas9, transcription activator-like effector nucleases (), meganucleases, and zinc finger nucleases (ZFN). [1]

  8. CRISPR gene-editing approved for first human trials - AOL

    www.aol.com/news/2016-06-22-crispr-gene-editing...

    A federal ethics and biosafety panel has approved the first ever human trials of the CRISPR-Cas9 gene editing technique. Researchers from the University of Pennsylvania aim to modify the immune ...

  9. Gain-of-function research - Wikipedia

    en.wikipedia.org/wiki/Gain-of-function_research

    On 19 December 2017, the NIH lifted the moratorium because gain-of-function research was deemed "important in helping us identify, understand, and develop strategies and effective countermeasures against rapidly evolving pathogens that pose a threat to public health."