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For example, hyaluronic acid is a major component of the synovial fluid and was found to increase the viscosity of the fluid. Along with lubricin, it is one of the fluid's main lubricating components. [citation needed] Hyaluronic acid is an important component of articular cartilage, where it is present as a coat around each cell (chondrocyte).
Hyaline cartilage is the glass-like and translucent cartilage found on many joint surfaces. It is also most commonly found in the ribs , nose, larynx , and trachea . [ 1 ] Hyaline cartilage is pearl-gray in color, with a firm consistency and has a considerable amount of collagen.
GAGs are polysaccharides that trap water, giving the ground substance a gel-like texture. Important GAGs found in ground substance include hyaluronic acid, heparan sulfate, dermatan sulfate, and chondroitin sulfate. With the exception of hyaluronic acid, GAGs are bound to proteins called proteoglycans.
In this test, acetic acid is added to the synovial fluid specimen. In a normal specimen, this should lead to a congealing of the hyaluronic acid, forming a 'mucin clot.' If inflammation is present, a mucin clot is not formed (the hyaluronic acid is degraded). [21] Lactate is elevated in septic arthritis, usually above 250 mg/dL.
The vomeronasal cartilage is a thin piece of hyaline cartilage that attaches to the vomer and extends to the septal nasal cartilage. [10] This structure is associated with the vomeronasal organ, which is part of the accessory olfactory system. This associated organ plays an important role in the sense of smell by being lined with similar ...
Aggrecan is a critical component for cartilage structure and the function of joints. Functionally, the G1 domain interacts with hyaluronic acid and link protein, forming stable ternary complexes in the extracellular matrix. G2 is homologous to the tandem repeats of G1 and of link protein and is involved in product processing.
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