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Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...
Its mechanism of action is thought to be due to antagonism of the postsynaptic T-type voltage-gated calcium channel. [6] Ethosuximide was approved for medical use in the United States in 1960. [7] It is on the World Health Organization's List of Essential Medicines. [8] Ethosuximide is available as a generic medication. [4]
Benzodiazepines act as a central nervous system depressant. The relative strength of each of these properties in any given benzodiazepine varies greatly and influences the indications for which it is prescribed. Long-term use can be problematic due to the development of tolerance to the anticonvulsant effects and dependency.
Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
Early decision (ED) or early acceptance is a type of early admission used in college admissions in the United States for admitting freshmen to undergraduate programs.It is used to indicate to the university or college that the candidate considers that institution to be their top choice through a binding commitment to enroll; in other words, if offered admission under an ED program, and the ...
Early entrance to college, sometimes called early admission or early enrollment, is the practice of allowing students to be accelerated into college, one or more years before the traditional age of college entrance, and without obtaining a high school diploma. In some cases this is done individually.
At times, TSAO schools adopt common policies with respect to applicants and admitted students, such as a uniform deadline to accept or reject offers of admission. [5] The TSAO does not have a uniform policy with respect to standardized testing, and two of its member schools remain test-optional as of the 2024-25 application cycle. [6] [7]
Early action (EA) is a type of early admission process offered by some institutions for admission to colleges and universities in the United States.Unlike the regular admissions process, EA usually requires students to submit an application by mid-October or early November of their senior year of high school instead of January 1.