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The method was first described in 2002 in the scientific journal Nucleic Acid Research. [2] The first applications included the detection of exon deletions in the human genes BRCA1, MSH2 and MLH1, which are linked to hereditary breast and colon cancer. Now MLPA is used to detect hundreds of hereditary disorders, as well as for tumour profiling.
Ploidy (/ ˈ p l ɔɪ d i /) is the number of complete sets of chromosomes in a cell, and hence the number of possible alleles for autosomal and pseudoautosomal genes. Here sets of chromosomes refers to the number of maternal and paternal chromosome copies, respectively, in each homologous chromosome pair—the form in which chromosomes ...
Laboratory methods and techniques, as used in fields like biology, biochemistry, biophysics, chemistry, molecular biology, etc. Wikimedia Commons has media related to Laboratory techniques . Contents
Molecular biology techniques are common methods used in molecular biology, biochemistry, genetics and biophysics which generally involve manipulation and analysis of DNA, RNA, protein, and lipid Wikimedia Commons has media related to Molecular biology techniques .
A polyploid complex, also called a diploid-polyploid complex, is a group of interrelated and interbreeding species that also have differing levels of ploidy that can allow interbreeding. A polyploid complex was described by E. B. Babcock and G. Ledyard Stebbins in their 1938 monograph The American Species of Crepis : their interrelationships ...
In natural and social science research, a protocol is most commonly a predefined procedural method in the design and implementation of an experiment.Protocols are written whenever it is desirable to standardize a laboratory method to ensure successful replication of results by others in the same laboratory or by other laboratories.
A simplification of an allopatric speciation experiment where two lines of fruit flies are raised on maltose and starch media. Laboratory experiments of speciation have been conducted for all four modes of speciation: allopatric, peripatric, parapatric, and sympatric; and various other processes involving speciation: hybridization, reinforcement, founder effects, among others.
Introduction to the Atomic Theory (1831); 2nd edition, 1850 [13] On the Action of Light upon Plants, and of Plants upon the Atmosphere (1836) Sketch of the Geology of North America (1839) Lectures on Agriculture (1841) Journal of a tour through the United States, and in Canada, made during the years 1837–38 (1843)