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2. Sildenafil - Wikipedia

   en.wikipedia.org/wiki/Sildenafil

   Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [ 4 ] [ 8 ] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon . [ 9 ]

3. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

   www.aol.com/4-common-ed-pills-weighing-141800609...

   Over the last 25 years, (ED) medications like Viagra and Cialis have become common fixtures in bedrooms around the world. ... from a longer duration of action to a reduced risk of side effects.

4. What Happens If You Take Viagra and You Don't Need It? - AOL

   www.aol.com/happens-viagra-dont-105800158.html

   Viagra could lead to more serious side effects, such as: Priapism (a painful, long-lasting arousal) Vision loss. Chest pain. Flu-like symptoms. Heart attack. Stroke. Dizziness. Sudden low blood ...

5. Is Sildenafil Safe for This Common Male Problem? - AOL

   www.aol.com/sildenafil-safe-common-male-problem...

   In fact, studies show that just one dose of Viagra has a 70 to 80 percent success rate for treating ED. PDE5 stands for phosphodiesterase type 5, an enzyme that plays an important role in ...

6. PDE5 inhibitor - Wikipedia

   en.wikipedia.org/wiki/PDE5_inhibitor

   Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

7. Pharmacodynamics - Wikipedia

   en.wikipedia.org/wiki/Pharmacodynamics

   The duration of action of a drug is the length of time that particular drug is effective. [5] Duration of action is a function of several parameters including plasma half-life, the time to equilibrate between plasma and target compartments, and the off rate of the drug from its biological target. [6]

8. What Does Viagra Actually Do to Your "Intimate" Experience? - AOL

   www.aol.com/does-viagra-actually-intimate...

   In clinical trials of Viagra, more than 82 percent of men with ED reported an improvement in their climaxes after using Viagra at a dosage of 100mg (the highest dosage prescribed for ED).

9. Prostaglandin E1 - Wikipedia

   en.wikipedia.org/wiki/Prostaglandin_E1

   Prostaglandin E 1 (PGE 1) is a naturally occurring prostaglandin and is also used as a medication (alprostadil). [2]In infants with congenital heart defects, it is delivered by slow injection into a vein to open the ductus arteriosus until surgery can be carried out. [3]