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A gallstone is a stone formed within the gallbladder from precipitated bile components. [2] The term cholelithiasis may refer to the presence of gallstones or to any disease caused by gallstones, [5] and choledocholithiasis refers to the presence of migrated gallstones within bile ducts.
In the human liver, bile is composed of 97–98% water, 0.7% bile salts, 0.2% bilirubin, 0.51% fats (cholesterol, fatty acids, and lecithin), and 200 meq/L inorganic salts. [ 2 ] [ 3 ] The two main pigments of bile are bilirubin , which is orange-yellow, and its oxidised form biliverdin , which is green.
As in other mammals, human thermoregulation is an important aspect of homeostasis. In thermoregulation, body heat is generated mostly in the deep organs, especially the liver, brain, and heart, and in contraction of skeletal muscles. [1] Humans have been able to adapt to a great diversity of climates, including hot humid and hot arid.
Also, humans had physiological mechanisms that reduced the rate of metabolism and that modified the sensitivity of sweat glands to provide an adequate amount for cooldown without the individual becoming dehydrated. [17] [20] There are two types of heat the body is adapted to, humid heat and dry heat, but the body adapts to both in similar ways.
Parts-per-million cube of relative abundance by mass of elements in an average adult human body down to 1 ppm. About 99% of the mass of the human body is made up of six elements: oxygen, carbon, hydrogen, nitrogen, calcium, and phosphorus. Only about 0.85% is composed of another five elements: potassium, sulfur, sodium, chlorine, and magnesium ...
3D still showing gallstones. Gallstones form when the bile is saturated, usually with either cholesterol or bilirubin. [20] Most gallstones do not cause symptoms, with stones either remaining in the gallbladder or passed along the biliary system. [21] When symptoms occur, severe "colicky" pain in the upper right quadrant of the abdomen is often ...
Human body temperature varies. It depends on sex, age, time of day, exertion level, health status (such as illness and menstruation), what part of the body the measurement is taken at, state of consciousness (waking, sleeping, sedated), and emotions. Body temperature is kept in the normal range by a homeostatic function known as ...
Synthesis of bile acids is a major route of cholesterol metabolism in most species other than humans. The body produces about 800 mg of cholesterol per day and about half of that is used for bile acid synthesis producing 400–600 mg daily. Human adults secrete between 12 and 18 g of bile acids into the intestine each day, mostly after meals.