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For example, endogenous substances, and endogenous processes are those that originate within a living system (e.g. an organism or a cell). For instance, estradiol is an endogenous estrogen hormone produced within the body, whereas ethinylestradiol is an exogenous synthetic estrogen, commonly used in birth control pills .
Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Homeostasis : regulation of the internal environment to maintain a constant state; for example, sweating to reduce temperature
Although the body is able to remove xenobiotics by reducing it to a less toxic form through xenobiotic metabolism then excreting it, it is also possible for it to be converted into a more toxic form in some cases. This process is referred to as bioactivation and can result in structural and functional changes to the microbiota. [2]
As an analytical technique, MS is a very sensitive method that requires very little sample (<1 ng of material or <10 μL of a biofluid) and can generate signals for thousands of metabolites from a single sample. MS instruments can also be configured for very high throughput metabolome analyses (hundreds to thousands of samples a day).
The destruction of these cells reduces the body's ability to respond to glucose levels in the body, therefore making it nearly impossible to properly regulate glucose and glucagon levels in the bloodstream. [25] The body destroys 70–80% of beta cells, leaving only 20–30% of functioning cells.
Ribbon representation of the Streptomyces lividans β-1,4-endoglucanase catalytic domain - an example from the family 12 glycoside hydrolases [1]. Cellulase (EC 3.2.1.4; systematic name 4-β-D-glucan 4-glucanohydrolase) is any of several enzymes produced chiefly by fungi, bacteria, and protozoans that catalyze cellulolysis, the decomposition of cellulose and of some related polysaccharides:
Anabolic processes build organs and tissues. These processes produce growth and differentiation of cells and increase in body size, a process that involves synthesis of complex molecules. Examples of anabolic processes include the growth and mineralization of bone and increases in muscle mass.
Urinary water loss, when the body water homeostat is intact, is a compensatory water loss, correcting any water excess in the body. However, since the kidneys cannot generate water, the thirst reflex is the all-important second effector mechanism of the body water homeostat, correcting any water deficit in the body.