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The cause of disease was tracked down using a genome-wide association study, which implicated a region on horse chromosome 25. [1] This chromosome was sequenced in five affected horses, [1] and in 2009, a mutation was discovered in the SLC5A3 gene. [4] Shortly after this, a genetic test was launched for horse owners to identify whether their ...
Equine encephalosis virus; Equine exertional rhabdomyolysis; Equine gastric ulcer syndrome; Equid alphaherpesvirus 1; Equid alphaherpesvirus 3; Equine infectious anemia; Equine influenza; Equine melanoma; Equine multinodular pulmonary fibrosis; Equine polysaccharide storage myopathy; Equine protozoal myeloencephalitis; Equine proximal enteritis ...
Lavender foal syndrome (LFS), also called coat color dilution lethal (CCDL), is an autosomal recessive genetic disease that affects newborn foals of certain Arabian horse bloodlines. Affected LFS foals have severe neurological abnormalities, cannot stand, and require euthanasia shortly after birth.
An equine melanoma is a tumor that results from the abnormal growth of melanocytes in horses. Unlike in humans, melanomas in horses are not thought to be caused by exposure to ultraviolet light. [1] Melanomas are the third most common type of skin cancer in horses, with sarcoids being the first most prevalent and squamous-cell carcinoma being ...
The Belgian Draft Horse is one breed in which JEB occurs Junctional epidermolysis bullosa ( JEB ) is an inherited disorder that is also known as red foot disease or hairless foal syndrome . [ 1 ] JEB is the result of a genetic mutation that inhibits protein production that is essential for skin adhesion. [ 2 ]
Equine sarcoid, a naturally occurring skin tumour affecting horses, donkeys and mules, is associated with strains of BPV-1/2 which may be equine specific. [11] The lesions can occur anywhere on the body, often multiply, with the limbs, thorax–abdomen, head and paragenital areas being particularly commonly affected.
Mare reproductive loss syndrome (MRLS) is a syndrome consisting of equine abortions and three related nonreproductive syndromes which occur in horses of all breeds, sexes, and ages. MRLS was first observed in the U.S. state of Kentucky in a three-week period around May 5, 2001, when about 20–30% of Kentucky's pregnant mares suffered abortions.
Skin cancer, or neoplasia, is the most common type of cancer diagnosed in horses, accounting for 45 [1] to 80% [2] of all cancers diagnosed. Sarcoids are the most common type of skin neoplasm and are the most common type of cancer overall in horses. Squamous-cell carcinoma is the second-most prevalent skin cancer, followed by melanoma. [3]