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P. aeruginosa is a Gram-negative, aerobic (and at times facultatively anaerobic), rod-shaped bacterium with unipolar motility. [80] It has been identified as an opportunistic pathogen of both humans and plants. [81] P. aeruginosa is the type species of the genus Pseudomonas. [82]
Biodiversity plays a vital role in maintaining human and animal health because numerous plants, animals, and fungi are used in medicine to produce vital vitamins, painkillers, antibiotics, and other medications. [1] [2] [3] Natural products have been recognized and used as medicines by ancient cultures all around the world. [4]
Sometimes, the term antibiotic—literally "opposing life", from the Greek roots ἀντι anti, "against" and βίος bios, "life"—is broadly used to refer to any substance used against microbes, but in the usual medical usage, antibiotics (such as penicillin) are those produced naturally (by one microorganism fighting another), whereas non ...
Anaerobic bacteria can be divided into strict anaerobes that can not grow in the presence of more than 0.5% oxygen and moderate anaerobic bacteria that are able of growing between 2 and 8% oxygen. [1] Anaerobic bacteria usually do not possess catalase, but some can generate superoxide dismutase which protects them from oxygen.
Antimicrobial use has been common practice for at least 2000 years. Ancient Egyptians and ancient Greeks used specific molds and plant extracts to treat infection. [5]In the 19th century, microbiologists such as Louis Pasteur and Jules Francois Joubert observed antagonism between some bacteria and discussed the merits of controlling these interactions in medicine. [6]
phytotherapy: the study of medicinal use of plant extracts; phytochemistry: the study of chemicals derived from plants (including the identification of new drug candidates derived from plant sources); zoopharmacognosy: the process by which animals self-medicate, by selecting and using plants, soils, and insects to treat and prevent disease;
In these cases it is often used in combination with metronidazole, which provides coverage for anaerobic pathogens. [7] complicated urinary tract infections, including acute pyelonephritis, in adults. hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia. [11]
Aminoglycoside antibiotics display bactericidal activity against Gram-negative aerobes and some anaerobic bacilli where resistance has not yet arisen but generally not against Gram-positive and anaerobic Gram-negative bacteria. [3] Streptomycin is the first-in-class aminoglycoside antibiotic.