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The bladder tumour antigen (BTA) test is used in the detection of bladder cancer.It works by detecting raised levels of complement factor Hârelated protein (CFHrp), which is produced by cancer cells, in urine.
Diagram showing the T stages of bladder cancer. Date: 30 July 2014 (released by CRUK) Source: Original email from CRUK: Author: Cancer Research UK: Permission (Reusing this file) This image has been released as part of an open knowledge project by Cancer Research UK. If re-used, attribute to Cancer Research UK / Wikimedia Commons
Bladder cancer is much more common in men than women; around 1.1% of men and 0.27% of women develop bladder cancer. [2] This makes bladder cancer the sixth most common cancer in men, and the seventeenth in women. [69] When women are diagnosed with bladder cancer, they tend to have more advanced disease and consequently a poorer prognosis. [69]
The test commonly checks for infection, inflammatory disease of the urinary tract, cancer, or precancerous conditions. It can be part of a broader urinalysis . If a cancerous condition is detected, other tests and procedures are usually recommended to diagnose cancers, including bladder cancer , ureteral cancer and cancer of the urethra .
Each assay may give different results of the clinical value of the p53 mutations as a prognostic factor. [5] Interlaboratory proficiency testing for tumor marker tests, and for clinical tests more generally, is routine in Europe and an emerging field [6] in the United States. New York state is prominent in advocating such research. [7]
loss of bladder control (incontinence) or overactive bladder; (Although, the American Urogynecologic Society does not recommend that cystoscopy, urodynamics, or diagnostic renal and bladder ultrasound are part of initial diagnosis for uncomplicated overactive bladder.) [2] [3] unusual cells found in urine sample; need for a bladder catheter;
Cancer/testis (CT) antigens are a group of proteins united by their importance in development and in cancer immunotherapy. In general, expression of these proteins is restricted to male germ cells in the adult animal. However, in cancer these developmental antigens are often re-expressed and can serve as a locus of immune activation.
An improper technique can produce false results, for example, leukocytes and erythrocytes precipitate at the bottom of the container and may not be detected if the sample is not properly mixed, and in the same way, if an excess of urine remains on the strip after it has been removed from the test sample, may cause the reagents to leak from the ...
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