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Dabigatran, sold under the brand name Pradaxa among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. [ 6 ] [ 7 ] Specifically it is used to prevent blood clots following hip or knee replacement and in those with a history of prior clots. [ 6 ]
In October 2010 the US FDA approved dabigatran etexilate for the prevention of stroke in patients with atrial fibrillation (AF). [ 6 ] [ 10 ] Many pharmaceutical companies have attempted to develop orally bioavailable DTI drugs but dabigatran etexilate is the only one to reach the market.
Dabigatran is an oral direct thrombin inhibitor. Dabigatran (Pradaxa) was found to be noninferior to Warfarin in prevention of ischemic stroke, as well as intracranial hemorrhage risk and overall mortality for non-valvular atrial fibrillation according to the RE-LY trial.
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Direct factor Xa inhibitors (xabans) are anticoagulants (blood thinning drugs), used to both treat and prevent blood clots in veins, and prevent stroke and embolism in people with atrial fibrillation (AF). [2] [3]
Collage of political strategist, Alex Bruesewitz, and other men in suits including Donald Trump, at the moment Bruesewitz collapsed during a speech.Alex Bruesewitz, a top adviser for President ...
[15] withdrawn from general use in UK but permitted in terminal patients Dexfenfluramine: 1997 European Union, UK, US Cardiotoxic [3] Propoxyphene (Darvocet/Darvon) 2010 Worldwide Increased risk of heart attacks and stroke. [16] Diacetoxydiphenolisatin: 1971 Australia Hepatotoxicity. [3] Diethylstilbestrol: 1970s US Carcinogen Difemerine: 1986 ...
(The Center Square) – Whether Illinois should be enjoined from enforcing the state’s gun and magazine ban starting Monday is now up to a federal appeals court. Illinois enacted the Protect ...