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  2. Deuterated drug - Wikipedia

    en.wikipedia.org/wiki/Deuterated_drug

    The deuterium isotope effect has become an important tool in the elucidation of the mechanism of chemical reactions. Deuterium contains one proton, one electron, and a neutron, effectively doubling the mass of the deuterium isotope without changing its properties significantly.

  3. Hydrogen–deuterium exchange - Wikipedia

    en.wikipedia.org/wiki/Hydrogen–deuterium_exchange

    The exchange reaction can be followed using a variety of methods (see Detection). Since this exchange is an equilibrium reaction, the molar amount of deuterium should be high compared to the exchangeable protons of the substrate. For instance, deuterium is added to a protein in H 2 O by diluting the H 2 O solution with D 2 O (e.g. tenfold ...

  4. Kathryn Beers - Wikipedia

    en.wikipedia.org/wiki/Kathryn_Beers

    She completed a B.S. in chemistry at the College of William & Mary in 1994. [2] Her Honors College undergraduate thesis was titled The effects of deuteration of ferromagnetic properties: a study of single crystal Fe[S 2 CN(C 2 D 5) 2] 2 Cl. [3] In 1996, she earned an M.S. in polymer science at Carnegie Mellon University. She completed a Ph.D ...

  5. Deuterium NMR - Wikipedia

    en.wikipedia.org/wiki/Deuterium_NMR

    It may be used to verify the effectiveness of deuteration: a deuterated compound will show a strong peak in 2 H NMR but not proton NMR. 2 H NMR spectra are especially informative in the solid state because of its relatively small quadrupole moment in comparison with those of bigger quadrupolar nuclei such as chlorine-35. This allows for the ...

  6. Deuterated acetone - Wikipedia

    en.wikipedia.org/wiki/Deuterated_acetone

    Deuterated acetone is prepared by the reaction of acetone with heavy water, 2 H 2 O or D 2 O, in the presence of a base. In this case, the base used is deuterated lithium hydroxide : [ 1 ] In order to fully deuterate the acetone, the process is repeated several times, distilling off the acetone from the heavy water, and re-running the reaction ...

  7. Deuterated benzene - Wikipedia

    en.wikipedia.org/wiki/Deuterated_benzene

    Deuterated benzene will undergo all the same reactions its normal analogue will, just a little more slowly due to the kinetic isotope effect. For example, deuterated benzene could be used in the synthesis of deuterated benzoic acid , if desired:

  8. Deuterated chloroform - Wikipedia

    en.wikipedia.org/wiki/Deuterated_chloroform

    Deuterated chloroform, also known as chloroform-d, is the organic compound with the formula CDCl 3.Deuterated chloroform is a common solvent used in NMR spectroscopy. [2] The properties of CDCl 3 and ordinary CHCl 3 are virtually identical.

  9. DABCO - Wikipedia

    en.wikipedia.org/wiki/DABCO

    DABCO (1,4-diazabicyclo[2.2.2]octane), also known as triethylenediamine or TEDA, is a bicyclic organic compound with the formula N 2 (C 2 H 4) 3.This colorless solid is a highly nucleophilic tertiary amine base, which is used as a catalyst and reagent in polymerization and organic synthesis.