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Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. [1] [9] People with latent TB do not spread the disease. [1] Active infection occurs more often in people with HIV/AIDS and in those who smoke. [1]
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [1] [2] First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid.
Since they were previously exposed, the immune system’s memory T cells quickly release cytokines to try and control the new outbreak, which forms more areas of caseous necrosis, this time, though, it tends to cavitate, or form cavities, which can allow the bacteria to disseminate, or spread through airways and lymphatic channels to other ...
An infectious disease agent can be transmitted in two ways: as horizontal disease agent transmission from one individual to another in the same generation (peers in the same age group) [3] by either direct contact (licking, touching, biting), or indirect contact through air – cough or sneeze (vectors or fomites that allow the transmission of the agent causing the disease without physical ...
Tuberculosis can also spread through the blood from the primary focus to elsewhere in the abdomen. Abdominal solid organs, kidneys, lymph nodes and peritoneum can be affected this way. [ 2 ] Tuberculosis is also reported to spread to the peritoneum directly from adjacently situated infected foci, such as from the fallopian tubes, adnexa, psoas ...
Fecal–oral transmission is primarily considered as an indirect contact route through contaminated food or water. However, it can also operate through direct contact with feces or contaminated body parts, such as through anal sex. [2] [3] It can also operate through droplet or airborne transmission through the toilet plume from contaminated ...
Mycobacterium tuberculosis is the most common cause of both pulmonary tuberculosis and tuberculous lymphadenitis. [1] [6] Historically, transmission of Mycobacterium bovis from dairy consumption was another frequent cause of tuberculous lymphadenitis, but incidence has drastically decreased in developed countries since the advent of pasteurization and other efforts to prevent bovine ...
malnutrition (which may be the result of illness or injury affecting the digestive system, or of a prolonged period of not eating, or disturbance in food availability such as during famine or residence in a refugee or concentration camp); degradation of the immune system due to aging; [14] certain systemic diseases such as diabetes,; [15]