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Atezolizumab, sold under the brand name Tecentriq among others, is a monoclonal antibody medication used to treat urothelial carcinoma, non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), hepatocellular carcinoma and alveolar soft part sarcoma, [9] [11] but discontinued for use in triple-negative breast cancer (TNBC). [12]
The subcutaneous injection of atezolizumab and hyaluronidase was evaluated in IMscin001 (NCT03735121), an open-label, multi-center, international, randomized trial in adults with locally advanced or metastatic non-small cell lung cancer who were not previously exposed to cancer immunotherapy and who had disease progression following treatment with platinum-based chemotherapy. [2]
Ongoing — COVID-19 pandemic in Kosovo 13 March – The first two cases of COVID-19 in the country were confirmed, a 77-year-old man from Vitina and an Italian woman in her early 20s, who worked in Klina with Caritas Kosova.
The study enrolled 34 patients, 28 of which underwent surgery to resect the PDAC. 19 of the patients who had undergone surgery then received atezolizumab, an immune checkpoint inhibitor. 16 of the patients on atezolizumab then received autogene cevumeran. 1 patient was considered to have insufficiently many neoantigens to manufacture the vaccine.
Map of the Autonomous Province of Kosovo and Metohija. The Autonomous Province of Kosovo and Metohija (Serbian: Косово и Метохиja, romanized: Kosovo i Metohija; Albanian: Kosova dhe Metohia), commonly known as Kosovo (Serbian: Косово; Albanian: Kosova) and abbreviated to Kosmet (from Kosovo and Metohija; Serbian: Космет) or KiM (Serbian: КиМ), is an autonomous ...
Bajram Rexhepi - Prime Minister of Kosovo 2002-2004 [18] Ibrahim Rugova - first president of Kosovo (1992–2000) and (2002–2006) [19] Fatmir Sejdiu - first president of the Republic of Kosovo (2006–2010) [20] Hashim Thaçi - former Prime Minister and President of Kosovo [20] Azem Vllasi - senior politician and lawyer [3]
Phase III clinical trials produced mixed results; and, on October 14, 2020, Hoffmann-La Roche, the parent company of Genentech, abandoned further efforts to develop etrolizumab for ulcerative colitis, but continued development for Crohn's disease, [8] until disappointing trial results led to this being abandoned too in February 2022.
President of Yugoslavia Josip Broz Tito visiting Brezovica in 1975.. In Medieval Serbia, the župa (province) of Sirinić (first mentioned in a charter of the 13th century, the second time in 1331, in a charter of Emperor Stephen Dušan) existed, covering the whole of modern Štrpce municipality, having the cities of Gradište (in Brezovica) and Zidinac (in Gotovuša).