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Orthostatic intolerance (OI) is the development of symptoms when standing upright that are relieved when reclining. [1] There are many types of orthostatic intolerance. OI can be a subcategory of dysautonomia , a disorder of the autonomic nervous system [ 2 ] occurring when an individual stands up. [ 3 ]
Suspension trauma, also known as orthostatic shock while suspended, harness hang syndrome (HHS), suspension syndrome, or orthostatic intolerance, is an effect which occurs when the human body is held upright without any movement for a period of time.
Treatment of dysautonomia can be difficult; since it is made up of many different symptoms, a combination of drug therapies is often required to manage individual symptomatic complaints. In the case of autoimmune neuropathy, treatment with immunomodulatory therapies is done. If diabetes mellitus is the cause, control of blood glucose is ...
Orthostatic hypertension involving the systolic BP is known as systolic orthostatic hypertension. High diastolic blood pressure measured while standing in a person who stood up shortly after waking up. When it affects an individual's ability to remain upright, orthostatic hypertension is considered as a form of orthostatic intolerance.
Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by an abnormally large increase in heart rate upon sitting up or standing. [1] POTS is a disorder of the autonomic nervous system that can lead to a variety of symptoms, [10] including lightheadedness, brain fog, blurred vision, weakness, fatigue, headaches, heart palpitations, exercise intolerance, nausea ...
Due to its effects on increasing Na+ levels, and therefore blood volume, fludrocortisone is the first-line of treatment for orthostatic intolerance, and postural orthostatic tachycardia syndrome (POTS). [11] It can be used to treat low blood pressure. [12]
Fludrocortisone is commonly used for patients with postural orthostatic tachycardia syndrome (POTS) to treat orthostatic intolerance. [56] Given the high comorbidity rate between ME/CFS and POTS, [57] it's possible that fludrocortisone could reduce symptoms in these patients. However, there is no research available which examines its effect on ...
Pyridostigmine sometimes is used to treat orthostatic hypotension. [10] It may also be of benefit in chronic axonal polyneuropathy. [11] It is also being prescribed off-label for postural orthostatic tachycardia syndrome (POTS) as well as complications resulting from Ehlers–Danlos syndrome. [11] [12]