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  2. Sulfinpyrazone - Wikipedia

    en.wikipedia.org/wiki/Sulfinpyrazone

    Sulfinpyrazone is a uricosuric medication used to treat gout. It also sometimes is used to reduce platelet aggregation by inhibiting degranulation of platelets which reduces the release of ADP and thromboxane. Like other uricosurics, sulfinpyrazone works by competitively inhibiting uric acid reabsorption in the proximal tubule of the kidney.

  3. Saroglitazar - Wikipedia

    en.wikipedia.org/wiki/Saroglitazar

    Saroglitazar is indicated for the treatment of diabetic dyslipidemia and hypertriglyceridemia with type 2 diabetes mellitus not controlled by statin therapy. In clinical studies, saroglitazar has demonstrated reduction of triglycerides (TG), LDL cholesterol , VLDL cholesterol, non-HDL cholesterol and an increase in HDL cholesterol a ...

  4. BGR-34 - Wikipedia

    en.wikipedia.org/wiki/BGR-34

    BGR-34 (Blood Glucose Regulator-34) [1] is an Ayurvedic-derived product that is sold in India as an over-the-counter pill for the management of type 2 diabetes.It was developed in 2015 by two government-owned laboratories and launched commercially in 2016.

  5. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    SGLT2 inhibitors are used in the treatment of type 2 diabetes. Apart from blood sugar control, gliflozins have been shown to provide significant cardiovascular benefit in people with type 2 diabetes. [2] [3] As of 2014, several medications of this class had been approved or were under development. [4]

  6. Dipeptidyl peptidase-4 inhibitor - Wikipedia

    en.wikipedia.org/wiki/Dipeptidyl_peptidase-4...

    Adverse effects include nasopharyngitis, headache, nausea, heart failure, hypersensitivity and skin reactions. [ citation needed ] The U.S. Food and Drug Administration (FDA) is warning that the type 2 diabetes medicines like sitagliptin , saxagliptin , linagliptin , and alogliptin may cause joint pain that can be severe and disabling.

  7. Probenecid - Wikipedia

    en.wikipedia.org/wiki/Probenecid

    Mild symptoms such as nausea, loss of appetite, dizziness, vomiting, headache, sore gums, or frequent urination are common with this medication. Life-threatening side effects such as thrombocytopenia, hemolytic anemia, leukemia and encephalopathy are extremely rare. [4] Theoretically probenecid can increase the risk of uric acid kidney stones.

  8. Nephrogenic diabetes insipidus - Wikipedia

    en.wikipedia.org/wiki/Nephrogenic_diabetes_insipidus

    Persons with nephrogenic diabetes insipidus must consume enough fluids to equal the amount of urine produced. Any underlying cause such as high blood calcium must be corrected to treat nephrogenic diabetes insipidus. The first line of treatment is hydrochlorothiazide and amiloride. [10] Patients may also consider a low-salt and low-protein diet.

  9. Thiazolidinedione - Wikipedia

    en.wikipedia.org/wiki/Thiazolidinedione

    Thiazolidinedione ligand dependent transactivation is responsible for the majority of anti-diabetic effects. The activated PPAR/RXR heterodimer binds to peroxisome proliferator hormone response elements upstream of target genes in complex with a number of coactivators such as nuclear receptor coactivator 1 and CREB binding protein, this causes upregulation of genes (for a full list see PPARγ):

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