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It particularly affects the skin around the mouth and distal extremities; but may also be found on the lower abdomen, buttocks, perineum, and groin. It is strongly associated with glucagonoma , a glucagon -producing tumor of the pancreas , but is also seen in a number of other conditions including liver disease and intestinal malabsorption .
Classic symptoms include, but are not limited to, necrolytic migratory erythema (NME), diabetes mellitus, and weight loss. [3] NME presents in about 70% of cases of glucagonoma, [4] and is characterized by erythematous lesions over the distal extremities and the groin area. [3] NME has occasionally been observed in people who do not have ...
The signs and symptoms listed below are relating to hematoceles and associated conditions that can be due to other causes such as testicular cancer or testicular torsion: [7] Unusual lump; Sudden pain; Dull aching pain or feeling heavy in the scrotum; Pain radiating throughout the groin, abdomen, or lower back; Tender, swollen, or hardened testicle
College student, 20, felt soreness in groin, thought it was pulled muscle. It was 1st sign of testicular cancer. ... said that there was blood flow to the area, which meant that it was probably ...
Pelvic pain is pain in the area of the pelvis. Acute pain is more common than chronic pain. [2] If the pain lasts for more than six months, it is deemed to be chronic pelvic pain. [3] [4] It can affect both the male and female pelvis. Common causes in include: endometriosis in women, bowel adhesions, irritable bowel syndrome, and interstitial ...
A cancer syndrome or family cancer syndrome is a genetic disorder in which inherited genetic mutations in one or more genes predisposes the affected individuals to the development of cancers and may also cause the early onset of these cancers. Although cancer syndromes exhibit an increased risk of cancer, the risk varies.
The base of the skull may be affected by metastases from cancer of the bronchus, breast or prostate, or cancer may spread directly to this area from the nasopharynx , and this may cause headache, facial paresthesia, dysesthesia or pain, or cranial nerve dysfunction – the exact symptoms depend on the cranial nerves impacted. [4]
A leiomyosarcoma (LMS) is a rare malignant (cancerous) smooth muscle tumor. [1] The word is from leio- 'smooth' myo- 'muscle' and sarcoma 'tumor of connective tissue'. The stomach, bladder, uterus, blood vessels, and intestines are examples of hollow organs made up of smooth muscles where LMS can be located; however, the uterus and abdomen are the most common sites.