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The NBOMe drugs are highly potent and selective agonists of the serotonin 5-HT 2 receptors, including of the 5-HT 2A, 5-HT 2B, and 5-HT 2C receptors. [1] [3] [12] [13] However, they are much less potent and efficacious at the serotonin 5-HT 2B receptor compared to the serotonin 5-HT 2A and 5-HT 2C receptors. [3]
Benzonitrile is a useful solvent and a versatile precursor to many derivatives. It reacts with amines to afford N-substituted benzamides after hydrolysis. [3] It is a precursor to diphenylmethanimine via reaction with phenylmagnesium bromide followed by methanolysis.
3.2 Multiplicative prefixes for naming assemblies of identical units. 4 Etymology. ... 20 icosa- 900 nonacta- 21 henicosa- 1000 kilia- 22 docosa- 2000 dilia- 23
Typical nitrile ligands are acetonitrile, propionitrile, and benzonitrile.The structures of [Ru(NH 3) 5 (NCPh)] n+ have been determined for the 2+ and 3+ oxidation states. Upon oxidation the Ru-NH 3 distances contract and the Ru-NCPh distances elongate, consistent with amines serving as pure-sigma donor ligands and nitriles functioning as pi-acceptors.
2,5-Dimethoxy-4-nitroamphetamine (DON) is a psychedelic drug and amphetamine. It is an analog of DOM and DOB. It is also closely related to 2C-N. Chemistry.
The nanometre (international spelling as used by the International Bureau of Weights and Measures; SI symbol: nm), or nanometer (American spelling), is a unit of length in the International System of Units (SI), equal to one billionth (short scale) or one thousand million (long scale) of a meter (0.000000001 m) and to 1000 picometres.
3,4-Dimethoxy-N-methylamphetamine (DMMA) is a psychoactive drug and research chemical of the phenethylamine and amphetamine chemical classes. It appears to act as a serotonin–norepinephrine–dopamine releasing agent (SNDRA), although it is significantly less potent than MDMA .
Several 5-HT 2A agonist hallucinogens including (R)-2,5-dimethoxy-4-iodoamphetamine DOI, TCB-2, LSD and LA-SS-Az have unexpectedly also been found to act as potent inhibitors of TNF, with DOI being the most active, showing TNF inhibition in the picomolar range, an order of magnitude more potent than its action as a hallucinogen. [8] [9] [10]