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However, the rates of these side effects with bicalutamide monotherapy are very low. [8] In the EPC trial, at 7.4 years follow-up, the rates of decreased libido and impotence were only 3.6% and 9.3% in the 150 mg/day bicalutamide monotherapy group relative to 1.2% and 6.5% for placebo, respectively. [ 8 ]
Tolterodine, sold under the brand name Detrol among others, is a medication used to treat frequent urination, urinary incontinence, or urinary urgency. [5] Effects are seen within an hour. [6] It is taken by mouth. [6] [7] Common side effects include headache, dry mouth, constipation, and dizziness. [6]
A 2006 cost-effectiveness study found that 5 mg solifenacin had the lowest cost and highest effectiveness among anticholinergic drugs used to treat overactive bladder in the United States, with an average medical cost per successfully treated patient of $6863 per year. [16]
Vibegron, sold under the brand name Gemtesa, is a medication for the treatment of overactive bladder. [1] [5] [6] Vibegron is a selective beta-3 adrenergic receptor agonist. [1] The most common side effects include headache, urinary tract infection, common cold, diarrhea, nausea, and upper respiratory tract infection. [5]
Outside the United States, PTNS is also used to treat fecal incontinence. PTNS can be used as a primary therapy. Treatment for overactive bladder and fecal incontinence may begin with pharmacological therapies before PTNS is administered. Unlike the variety of OAB drugs available PTNS is more effective and produces far fewer side-effects. [1]
fewer side effects than short-acting Oxybutynin; 2 pills per day; 10% of Caucasians and 19% of black people have a genetic difference which causes them to lack a certain enzyme. Lack of this enzyme makes the drug less effective. Tolterodine (extended release) fewer side effects than short-acting Oxybutynin; 1 pill per day
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