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Radiation enteropathy represents the longer-term, chronic effects that may be found after a latent period most commonly of 6 months to 3 years after the end of treatment. In some cases, it does not become a problem for 20–30 years after successful curative therapy.
Radiation proctitis or radiation proctopathy is a condition characterized by damage to the rectum after exposure to x-rays or other ionizing radiation as a part of radiation therapy. [1] Radiation proctopathy may occur as acute inflammation called "acute radiation proctitis" (and the related radiation colitis) or with chronic changes ...
Treatment of immune checkpoint inhibitor colitis is based on severity, as defined by the grade of diarrhea and colitis. Mild cases by managed with temporary interruption of immune checkpoint inhibitor therapy, dietary modification (low residue), and/or loperamide. More severe cases require immune suppression with corticosteroid therapy.
[5] In 2014, Akleyev's book "Comprehensive analysis of chronic radiation syndrome, covering epidemiology, pathogenesis, pathoanatomy, diagnosis and treatment" was published by Springer. [6] Symptoms of chronic radiation syndrome would include, at an early stage, impaired sense of touch and smell and disturbances of the vegetative functions.
Radiation colitis is injury to the colon caused by radiation therapy. It is usually associated with treatment for prostate cancer or cervical cancer . [ 1 ] Common symptoms are diarrhea , a feeling of being unable to empty the bowel , [ 2 ] gastrointestinal bleeding, and abdominal pain.
Early radiation enteritis is caused by cell death of the crypt epithelium and subsequent mucosal inflammation, however usually subsides after the course of radiation therapy is completed. Delayed radiation enteritis is a chronic disease which has a complex pathogenesis involving changes in the majority of the intestinal wall. [19] [20]
21% of Americans have chronic pain. A new study found that diets rich in vegetables, fruits, grains, lean proteins, and dairy was linked to less chronic pain.
Radiation enteropathy [7] Chronic enteropathy associated with SLCO2A1 gene; If the condition also involves the stomach, it is known as "gastroenteropathy". In pigs, porcine proliferative enteropathy is a diarrheal disease. [8]