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Radioactive iodine (iodine-131) alone can potentially worsen thyrotoxicosis in the first few days after treatment. One side effect of treatment is an initial period of a few days of increased hyperthyroid symptoms. This occurs because when the radioactive iodine destroys the thyroid cells, they can release thyroid hormone into the blood stream.
In older patients, emotional instability may be less evident, or depression may occur, and the symptoms and signs are manifestly circulatory. In many, the thyroid is not readily palpable. [4] Symptoms such as rapid heart rate, shortness of breath on exertion, and edema may predominate. Older patients also tend to have more weight loss and less ...
Acute radiation syndrome (ARS), also known as radiation sickness or radiation poisoning, is a collection of health effects that are caused by being exposed to high amounts of ionizing radiation in a short period of time. [1]
The absolute indications are a large goiter (especially when compressing the trachea), suspicious nodules or suspected cancer (to pathologically examine the thyroid), and people with ophthalmopathy and additionally if it is the person's preferred method of treatment or if refusing to undergo radioactive iodine treatment. Pregnancy is advised to ...
Screening people without symptoms and at normal risk for the disease is not recommended. [10] [11] Treatment options may include surgery, radiation therapy including radioactive iodine, chemotherapy, thyroid hormone, targeted therapy, and watchful waiting. [1] Surgery may involve removing part or all of the thyroid. [4]
Radioactive iodine-131 is a common fission product; it was a major component of the radioactivity released from the Chernobyl disaster, leading to nine fatal cases of pediatric thyroid cancer and hypothyroidism. On the other hand, radioactive iodine is used in the diagnosis and treatment of many diseases of the thyroid precisely because of the ...
Variability also exists between treatment and non-treatment groups in the use of radio-iodine and post-treatment thyroid stimulating hormone (TSH) suppression and treatment techniques between and within retrospective studies. Some recent studies have indicated that EBRT may be promising, though the number of patients studies has been small. [12]
Iodine-124 can be made by numerous nuclear reactions via a cyclotron. The most common starting material used is 124 Te. Iodine-124 as the iodide salt can be used to directly image the thyroid using positron emission tomography (PET). [9] Iodine-124 can also be used as a PET radiotracer with a usefully longer half-life compared with fluorine-18 ...