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Electrical cell fusion is an essential step in some of the most innovative methods in modern biology. This method begins when two cells are brought into contact by dielectrophoresis . Dielectrophoresis uses a high frequency alternating current, unlike electrophoresis in which a direct current is applied.
A syncytium (/ s ɪ n ˈ s ɪ ʃ i ə m /; pl.: syncytia; from Greek: σύν syn "together" and κύτος kytos "box, i.e. cell") or symplasm is a multinucleate cell that can result from multiple cell fusions of uninuclear cells (i.e., cells with a single nucleus), in contrast to a coenocyte, which can result from multiple nuclear divisions without accompanying cytokinesis. [1]
This glossary of cellular and molecular biology is a list of definitions of terms and concepts commonly used in the study of cell biology, molecular biology, and related disciplines, including molecular genetics, biochemistry, and microbiology. [1] It is split across two articles:
Heterokaryon in fungal mitosis. A heterokaryon is a multinucleate cell that contains genetically different nuclei. Heterokaryotic and heterokaryosis are derived terms. This is a special type of syncytium.
Cell fusion is the formation of a hybrid cell from two separate cells. [1] [2] There are three major actions taken in both virus–cell fusion and cell–cell fusion: the dehydration of polar head groups, the promotion of a hemifusion stalk, and the opening and expansion of pores between fusing cells. [3]
Cell–cell fusogens are proteins that promote plasma membrane fusion among different cells. To be considered a fusogen, it must be required for fusion, fuse unfamiliar membranes, and be present on the fusing membrane when need be. These cells include but are not limited too: gametes, trophoblasts, epithelial, and other developmental cells.
[11] [12] Other examples include the skeletal muscle cells of mammals, the tapetal cells of plants, and the storage cells of Douglas-fir seeds. [13] The polymorphonuclear leukocytes of mammals are not polynuclear cells, although the lobes of their nuclei are so deeply bifurcated that they can appear so under non-optimal microscopy.
In genetics, a fusion gene is a hybrid gene formed from two previously independent genes. It can occur as a result of translocation , interstitial deletion , or chromosomal inversion . Fusion genes have been found to be prevalent in all main types of human neoplasia . [ 1 ]