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Increased arterial stiffness is associated with an increased risk of cardiovascular events such as myocardial infarction, hypertension, heart failure, and stroke. [ 3 ] [ 4 ] [ 5 ] The World Health Organization identified cardiovascular disease as the leading cause of death globally in 2019.
Standing places significant pressure on the joint of the hips, knees, ankle and feet but without any significant movement of it. [9] This reduces the normal lubrication and cushioning of synovial joints, causing them to tear. The combined effect of pressure and tearing can cause extensive amounts of pain and make it difficult to move or walk. [3]
This testing uncovered calcified arteries and a collection of soft tissue near the femoral arteries and veins, which lead to a disruption in the right femoral artery. Extensive analysis of the individual's condition lead medical professionals to the conclusion that Mönckeberg's arteriosclerosis was suspected as the cause for their symptoms.
Other causes include vasculitis and in situ thrombosis related to hypercoagulable states. [53] Additional mechanisms of peripheral artery disease include arterial spasm and fibromuscular dysplasia. [19] The cause and pathophysiology of arterial spasm are not fully understood, but it is hypothesised that they can occur secondary to trauma. [54]
The arterial compliance - the amount of tension produced per stretch of arteries, decreases with age, and the stiffness of arteries increases with age. [3] The structural change in blood vessels causes the elderly to be more susceptible to hypertension, which leads to complications in arteries, the heart and even the brain. [citation needed]
Arteriosclerosis, literally meaning "hardening of the arteries", is an umbrella term for a vascular disorder characterized by abnormal thickening, hardening, and loss of elasticity [3] of the walls of arteries; [4] this process gradually restricts the blood flow to one's organs and tissues and can lead to severe health risks brought on by atherosclerosis, which is a specific form of ...
Also arterial hyalinosis and arteriolar hyalinosis refers to thickening of the walls of arterioles by the deposits that appear as homogeneous pink hyaline material in routine staining. [3] It is a type of arteriolosclerosis, which refers to thickening of the arteriolar wall and is part of the aging process.
A diagram explaining factors affecting arterial pressure. Pathophysiology is a study which explains the function of the body as it relates to diseases and conditions. The pathophysiology of hypertension is an area which attempts to explain mechanistically the causes of hypertension, which is a chronic disease characterized by elevation of blood pressure.
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