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13629 Ensembl ENSG00000167658 ENSMUSG00000034994 UniProt P13639 P58252 RefSeq (mRNA) NM_001961 NM_007907 RefSeq (protein) NP_001952 NP_031933 Location (UCSC) Chr 19: 3.98 – 3.99 Mb Chr 10: 81.01 – 81.02 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. It is the archaeal and eukaryotic ...
The steps in this microcycle are (1) positioning the correct aminoacyl-tRNA in the A site of the ribosome, which is brought into that site by eEF1, (2) forming the peptide bond, and (3) shifting the mRNA by one codon relative to the ribosome with the help of eEF2. Unlike bacteria, in which translation initiation occurs as soon as the 5' end of ...
Elongation is the most rapid step in translation. [3] In bacteria , it proceeds at a rate of 15 to 20 amino acids added per second (about 45-60 nucleotides per second). [ citation needed ] In eukaryotes the rate is about two amino acids per second (about 6 nucleotides read per second).
eIF2 is a heterotrimer of a total molar mass of 126 kDa that is composed of the three sub-units: α (sub-unit 1), β (sub-unit 2), and γ (sub-unit 3). The sequences of all three sub-units are highly conserved (pairwise amino acid identities for each sub-unit range from 47 to 72% when comparing the proteins of Homo sapiens and Saccharomyces cerevisiae).
EEF2: ENST00000309311: Eukaryotic translation elongation factor 2: chr19 GABARAP: ENST00000577035: GABA type A receptor-associated protein: chr17 PFDN5: ENST00000334478: Prefoldin subunit 5: chr12 RHOA: ENST00000418115: Ras homolog family member A: chr3 ubiquitin C: ENST00000546120: Ubiquitin C: chr12
13631 Ensembl ENSG00000103319 ENSG00000284161 ENSMUSG00000035064 UniProt O00418 O08796 RefSeq (mRNA) NM_013302 NM_001267710 NM_001267711 NM_007908 RefSeq (protein) NP_037434 NP_001254639 NP_001254640 NP_031934 Location (UCSC) Chr 16: 22.21 – 22.29 Mb Chr 7: 120.44 – 120.51 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Eukaryotic elongation factor-2 kinase (eEF-2 kinase or eEF ...
For example, the Shema, a central prayer in Judaism, is translated from Hebrew as “Hear, O Israel,” she said. Brooks said at Congregation Bene Shalom, they sign this as “pay attention Israel
The ribosome is a prominent drug target for antibacterials, which interfere with translation at different stages of the elongation cycle [44] Most clinically relevant translation compounds are inhibitors of bacterial translation, but inhibitors of eukaryotic translation may also hold therapeutic potential for application in cancer or antifungal ...