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Throughout her tenure at the University of Rochester, Gorbunova's research team continued to focus on the naked mole rat as a key to understanding cancer resistance among animals. In 2013, Gorbunova and Seluanov identified high molecular weight hyaluronan as the key mediator of cancer resistance in the naked mole rat. [9]
The naked mole-rat (Heterocephalus glaber), also known as the sand puppy, [6] is a burrowing rodent native to the Horn of Africa and parts of Kenya, notably in Somali regions. It is closely related to the blesmols and is the only species in the genus Heterocephalus .
It may look like a whiskered cocktail sausage, but the naked mole rat's incredible biology may one day improve countless lives. Meet the naked mole-rat: impervious to pain and cancer, and lives ...
The first animal to be photographed for the project was the naked mole-rat living at the Lincoln Children's Zoo. [8] In September 2017, the 7,000th animal photographed for the project was announced: the Leadbeater's possum, a critically endangered marsupial which is native to the acacia forests of central Victoria in Australia. [12]
The closely related subfamily Spalacinae consists of mole-like rodents found in Africa and the Middle East; these are also myomorphic rodents. The family Bathyergidae , or African mole-rats (including the well-known naked mole-rat ), belong to the other major division of the rodents, the hystricomorphs.
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Cells of naked mole rats, a species in which cancer has never observed, show hypersensitivity to contact inhibition. [8] This finding may provide a clue to cancer resistance. Furthermore, recent studies have further revealed some mechanisms of contact inhibition of proliferation and its potential implications in cancer therapy.
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