Search results
Results from the WOW.Com Content Network
EF-G catalyzes the translocation of the tRNA and mRNA down the ribosome at the end of each round of polypeptide elongation. [1] In this process, the peptidyl transferase center (PTC) has catalyzed the formation of a peptide bond between amino acids, moving the polypeptide chain from the P site tRNA to the A site tRNA. The 50S and 30S ribosomal ...
13629 Ensembl ENSG00000167658 ENSMUSG00000034994 UniProt P13639 P58252 RefSeq (mRNA) NM_001961 NM_007907 RefSeq (protein) NP_001952 NP_031933 Location (UCSC) Chr 19: 3.98 – 3.99 Mb Chr 10: 81.01 – 81.02 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. It is the archaeal and eukaryotic ...
EF-Tu (elongation factor thermo unstable) is a prokaryotic elongation factor responsible for catalyzing the binding of an aminoacyl-tRNA (aa-tRNA) to the ribosome. It is a G-protein , and facilitates the selection and binding of an aa-tRNA to the A-site of the ribosome.
Elongation is the most rapid step in translation. [3] In bacteria , it proceeds at a rate of 15 to 20 amino acids added per second (about 45-60 nucleotides per second). [ citation needed ] In eukaryotes the rate is about two amino acids per second (about 6 nucleotides read per second).
Elongation factor 1-alpha 1 (eEF1a1) is a translation elongation protein, expressed across eukaryotes. In humans, it is encoded by the EEF1A1 gene. [5] [6] This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha ...
The elongation and membrane targeting stages of eukaryotic translation. The ribosome is green and yellow, the tRNAs are dark-blue, and the other proteins involved are light-blue. Elongation depends on eukaryotic elongation factors. At the end of the initiation step, the mRNA is positioned so that the next codon can be translated during the ...
EC 7.2.1 Translocation of inorganic cations linked to oxidoreductase reactions; EC 7.2.2 Translocation of inorganic cations linked to the hydrolysis of a nucleoside triphosphate; EC 7.2.4 Translocation of inorganic cations linked to decarboxylation; An important translocase contained in this group is Na+/K+ pump, also known as EC 7.2.2.13.
In eukaryotes, SRP binds to the signal sequence of a newly synthesized peptide as it emerges from the ribosome. [1] This binding leads to the slowing of protein synthesis known as "elongation arrest", a conserved function of SRP that facilitates the coupling of the protein translation and the protein translocation processes. [5]