Search results
Results from the WOW.Com Content Network
In prokaryotes, corepressors are small molecules whereas in eukaryotes, corepressors are proteins. A corepressor does not directly bind to DNA, but instead indirectly regulates gene expression by binding to repressors. A corepressor downregulates (or represses) the expression of genes by binding to and activating a repressor transcription factor.
Transcriptional repression by corepressors is in many ways conceptually comparable to the mediation of receptor transcriptional activation by coactivators, but has an opposite outcome. Recruitment of corepressors, generally occurring in the absence of ligand, depends on a critical conformation of the receptor AF-2 domain, as well as upon ...
Current Neurology and Neuroscience Reports is a monthly peer-reviewed medical journal covering research in neurology and neuroscience. It is published by Springer Science+Business Media and the editors-in-chief are Stanley Fahn and John C. M. Brust ( Columbia University College of Physicians and Surgeons ).
transcription factor – a protein that binds to DNA and regulates gene expression by promoting or suppressing transcription transcriptional regulation – controlling the rate of gene transcription for example by helping or hindering RNA polymerase binding to DNA
Impact factor. 4.7 (2022) Standard abbreviations ... Neuropharmacology is a peer-reviewed scientific journal in the field of neuroscience.
The nuclear receptor co-repressor 2 is a transcriptional coregulatory protein that contains several nuclear receptor-interacting domains.In addition, NCOR2 appears to recruit histone deacetylases to DNA promoter regions.
23186 217864 Ensembl ENSG00000089902 ENSMUSG00000037896 UniProt Q9UKL0 Q8CFE3 RefSeq (mRNA) NM_015156 NM_198023 RefSeq (protein) NP_055971 NP_932140 Location (UCSC) Chr 14: 102.59 – 102.73 Mb Chr 12: 111.01 – 111.08 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse REST corepressor 1 also known as CoREST is a protein that in humans is encoded by the RCOR1 gene. Function This gene ...
Current Opinion in Neurology is a bimonthly peer-reviewed medical journal covering neurology.The journal publishes editorials and reviews, but not original research articles. . It is published by Lippincott Williams & Wilkins and the editor-in-chief is Richard S.J. Frackowiak (University College Londo