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  2. Electrolyte imbalance - Wikipedia

    en.wikipedia.org/wiki/Electrolyte_imbalance

    The levels of chloride in the blood can help determine if there are underlying metabolic disorders. [20] Generally, chloride has an inverse relationship with bicarbonate, an electrolyte that indicates acid-base status. [20] Overall, treatment of chloride imbalances involve addressing the underlying cause rather than supplementing or avoiding ...

  3. Short-term effects of alcohol consumption - Wikipedia

    en.wikipedia.org/wiki/Short-term_effects_of...

    The excess amount of blood aldehyde produce facial flushing, nausea, rapid heartbeat, and other adverse effects. [26] [27] Presence of these alleles causes rapid conversion of alcohol to acetaldehyde which can be toxic in large amount. So, the East Asians and Africans feel the adverse effects of alcohol early and stop drinking.

  4. Kindling (sedative–hypnotic withdrawal) - Wikipedia

    en.wikipedia.org/wiki/Kindling_(sedative...

    Binge drinking regimes are associated with causing an imbalance between inhibitory and excitatory amino acids and changes in monoamine release in the central nervous system, which increases neurotoxicity; this may result in cognitive impairments, psychological problems, and may cause irreversible brain damage in both adolescent and adult long-term binge drinkers.

  5. Alcohol and health - Wikipedia

    en.wikipedia.org/wiki/Alcohol_and_health

    Regular heavy drinking and heavy episodic drinking (also called binge drinking), entailing four or more standard alcoholic drinks (a pint of beer or 50 ml drink of a spirit such as whisky corresponds to about two units of alcohol) on any one occasion, pose the greatest risk for harm, but lesser amounts can cause problems as well. [55]

  6. First pass effect - Wikipedia

    en.wikipedia.org/wiki/First_pass_effect

    [1] [2] The effect is most associated with orally administered medications, but some drugs still undergo first-pass metabolism even when delivered via an alternate route (e.g., IV, IM, etc.). [3] During this metabolism, drug is lost during the process of absorption which is generally related to the liver and gut wall. The liver is the major ...

  7. Clinical vampirism - Wikipedia

    en.wikipedia.org/wiki/Clinical_vampirism

    Clinical vampirism, more commonly known as Renfield's syndrome, is an obsession with drinking blood.The earliest presentation of clinical vampirism in psychiatric literature was a psychoanalytic interpretation of two cases, contributed by Richard L. Vanden Bergh and John. F. Kelley. [1]

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  9. Alcohol intoxication - Wikipedia

    en.wikipedia.org/wiki/Alcohol_intoxication

    Some effects of alcohol intoxication, such as euphoria and lowered social inhibition, are central to alcohol's desirability. [21] As drinking increases, people become sleepy or fall into a stupor. At very high blood alcohol concentrations, for example above 0.3%, the respiratory system becomes depressed and the person may stop breathing. [22]