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The Lupus Research Alliance has given more money to lupus research than any non-governmental agency in the world. [4] As of 2015 the LRA's cumulative research commitment was over $100,000,000, [ 1 ] making it the largest lupus research organization and the only organization the funds lupus biomedical research internationally.
Lupus is Latin for "wolf", [154] [10] and in Medieval Latin was also used to refer to a disease of the skin, [155] and "erythematosus" is derived from ἐρύθημα, Ancient Greek for "redness of the skin". All explanations originate with the reddish, butterfly-shaped malar rash that the disease classically exhibits across the nose and cheeks.
Lupus is a peer-reviewed academic journal that publishes papers in the field of rheumatology. The journal's editor is Graham R. V. Hughes ( King's College London ). It has been in publication since 1991 and is currently published by SAGE Publishing .
Neuropsychiatric systemic lupus erythematosus or NPSLE refers to the neurological and psychiatric manifestations of systemic lupus erythematosus. SLE is a disease in which the immune system attacks the body's own cells and tissues.
Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints , skin , kidneys , blood cells , heart , and lungs .
Lupus erythematosus panniculitis may impact both sexes, but women are more likely to experience it. The percentages of frequency in case series vary, with different reports having female-to-male ratios of 2:1, 3:1, 4:1, and 9:1.
A ratio of 1.2 is commonly used, such that a value <1.2 indicates the absence of a lupus anticoagulant, while a value >1.2 indicates the presence of a lupus anticoagulant. [19] Direct oral anticoagulants and vitamin K antagonists used to treat thrombosis can interfere with lupus anticoagulant assays and generate either false-positive or false ...
The proliferative forms of lupus nephritis are associated with a higher risk of progression to end stage kidney disease. [21] Black and Hispanic people with lupus nephritis are more likely to present with severe disease at initial presentation (with more proteinuria and more extensive histopathologic changes) and progress to end stage kidney ...