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It is more effective where symptoms of catatonia are present, [170] and is recommended for use under NICE guidelines in the UK for catatonia if previously effective, though there is no recommendation for use for schizophrenia otherwise. [171] Psychosurgery has now become a rare procedure and is not a recommended treatment for schizophrenia. [172]
She founded the first scientific data to suggest that patients with treatment resistant schizophrenia do not have dopaminergic abnormality, and that the majority of these patients do not respond to treatment from the initial phases of their illness. [4] She has also won a Scholarship Award for Best Article in 2022 (Editors’ Choice). [5]
The effectiveness of xanomeline/trospium chloride for the treatment of schizophrenia in adults was evaluated in two studies with identical designs. [2] Study 1 (NCT04659161) and study 2 (NCT04738123) were 5-week, randomized, double-blind, placebo-controlled, multi-center studies in adults with a diagnosis of schizophrenia according to DSM-5 ...
Antipsychotic drug treatment is a key component of schizophrenia treatment recommendations by the National Institute of Health and Care Excellence (NICE), [23] the American Psychiatric Association, [24] and the British Society for Psychopharmacology. [25]
ECT is widely used worldwide in the treatment of schizophrenia, but in North America and Western Europe it is invariably used only in treatment resistant schizophrenia when symptoms show little response to antipsychotics; there is comprehensive research evidence for such practice. [55]
In 1986, the Northwick Park study [37] discovered an association between delays to treatment and disability, questioning the service provision for those with their first episode of schizophrenia. In the 1990s, evidence began to emerge that cognitive behavioural therapy was an effective treatment for delusions and hallucinations .
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