Search results
Results from the WOW.Com Content Network
Down syndrome or Down's syndrome, [12] also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. [3] It is usually associated with developmental delays, mild to moderate intellectual disability , and characteristic physical features.
Down Syndrome is a genetic disorder that was first described in 1866 by British doctor John L. Down. [2] It was discovered to be caused by an extra chromosome by French pediatrician Jérôme Lejeune in July 1958, less than two years before Tricia was born. [3] Medical advice in 1960 was typically to institutionalize children with Down Syndrome.
Developmental disability is a diverse group of chronic conditions, comprising mental or physical impairments that arise before adulthood. Developmental disabilities cause individuals living with them many difficulties in certain areas of life, especially in "language, mobility, learning, self-help, and independent living". [1]
The age of diagnosis can range from 9 months to 14 years, and the mean age is 4 years old in the USA. [11] On average each case of ASD is tested at three different diagnostic centers before confirmed. Early diagnosis of the disorder can diminish familial stress, speed up referral to special educational programs and influence family planning. [12]
After scientists in France discovered that people with Down syndrome had 47 chromosomes instead of the normal 46, she decided to investigate the cause of the extra chromosome. Cytogenetics , the study of chromosomes in cells, focuses on the identification and behavior of chromosomes, and Dr. Uchida was the first scientist to bring this ...
Research has found that there is a correlation between advanced paternal age and risk of birth defects such as limb anomalies, syndromes involving multiple systems, and Down syndrome. [74] [35] [93] Recent studies have concluded that 5-9% of Down syndrome cases are due to paternal effects, but these findings are controversial. [74] [75] [35] [94]
Brushfield spots are a characteristic feature of the chromosomal disorder Down syndrome or trisomy 21. They occur in 35–78% of newborn infants with Down syndrome. [ 2 ] Brushfield spots tend to be obscured by pigmentation of the anterior border layer of the iris in patients with darker irides.
In recent years, early childhood education [4] has become a prevalent public policy issue, as funding for preschool and pre-K is debated by municipal, state, and federal lawmakers. [ 5 ] [ 6 ] [ 7 ] Governing entities are also debating the central focus of early childhood education with debate on developmental appropriate play versus strong ...