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Axonotmesis mainly follows a stretch injury. These stretch injuries can either dislocate joints or fracture a limb, due to which peripheral nerves are severed. If the sharp pain from the exposed axon of the nerve is not observed, one can identify a nerve injury from abnormal sensations in their limb.
The actual mechanism behind the catastrophic brain swelling is controversial. [23] [24] A second injury during this time is thought to unleash a series of metabolic events within the brain. [25] [better source needed] Changes indicative of SIS may begin occurring in the injured brain within 15 seconds of the second concussion. [26]
Focal and diffuse brain injury are ways to classify brain injury: focal injury occurs in a specific location, while diffuse injury occurs over a more widespread area. It is common for both focal and diffuse damage to occur as a result of the same event; many traumatic brain injuries have aspects of both focal and diffuse injury. [ 1 ]
Primary and secondary brain injury are ways to classify the injury processes that occur in brain injury. In traumatic brain injury (TBI), primary brain injury occurs during the initial insult, and results from displacement of the physical structures of the brain. [1] Secondary brain injury occurs gradually and may involve an array of cellular ...
A traumatic brain injury (TBI), also known as an intracranial injury, is an injury to the brain caused by an external force. TBI can be classified based on severity ranging from mild traumatic brain injury (mTBI/concussion) to severe traumatic brain injury. [ 5 ]
The pathophysiology of obesity involves many possible pathophysiological mechanisms involved in its development and maintenance. [28] [29] This field of research had been almost unapproached until the leptin gene was discovered in 1994 by J. M. Friedman's laboratory. [30] These investigators postulated that leptin was a satiety factor.
Injury is physiological damage to the living tissue of any organism, whether in humans, in other animals, or in plants. Injuries can be caused in many ways, including mechanically with penetration by sharp objects such as teeth or with blunt objects , by heat or cold, or by venoms and biotoxins .
Nerve injury is an injury to a nerve.There is no single classification system that can describe all the many variations of nerve injuries. In 1941, Herbert Seddon introduced a classification of nerve injuries based on three main types of nerve fiber injury and whether there is continuity of the nerve. [1]