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  2. CYB004 - Wikipedia

    en.wikipedia.org/wiki/CYB004

    As with DMT, CYB004 is a potent agonist of the serotonin 5-HT 2A receptor and produces psychedelic-like effects in animals. [ 1 ] [ 5 ] [ 3 ] However, CYB004, due to its deuteration, is more resistant to metabolism than DMT and shows a longer elimination half-life (by 2.5- to 2.9-fold) and slower clearance (by 38 to 55%) in animals. [ 3 ]

  3. 5-MeO-DMT - Wikipedia

    en.wikipedia.org/wiki/5-MeO-DMT

    5-MeO-DMT is being developed and evaluated for potential therapeutic effects in patients with treatment-resistant depression (TRD). [57] Biopharmaceutical company GH Research has sponsored a completed phase 1 study in healthy volunteers [ 58 ] and phase 1/2 study in TRD patients where 87.5% of patients with TRD were brought into remission on ...

  4. Psychedelic therapy - Wikipedia

    en.wikipedia.org/wiki/Psychedelic_therapy

    These two studies are some of the first large controlled studies measuring the effects of psychedelic therapy on depression and anxiety in cancer patients. [66] Across clinician-ratings and self-ratings, the psychedelic treatment produced statistically significant lowered anxiety and depression, with sustenance for at least 6 months.

  5. How to Get These Anxiety Meds From a Doctor - AOL

    www.aol.com/different-types-anxiety-meds-them...

    Anxiety Medications: An Overview. Anxiety disorders are very common, according to the National Institute of Mental Health. An estimated 31.1 percent of all American adults will experience some ...

  6. 6-MeO-DMT - Wikipedia

    en.wikipedia.org/wiki/6-MeO-DMT

    6-MeO-DMT, or 6-methoxy-N,N-dimethyltryptamine, also known as 6-OMe-DMT, is a serotonergic drug of the tryptamine family. [ 1 ] [ 2 ] It is the 6- methoxy derivative of the serotonergic psychedelic N , N -dimethyltryptamine (DMT) and is a positional isomer of the serotonergic psychedelic 5-MeO-DMT .

  7. N,N-Dimethyltryptamine - Wikipedia

    en.wikipedia.org/wiki/N,N-Dimethyltryptamine

    [164] [166] [167] Similarly to DMT, 5-MeO-DMT is a biased agonist of the serotonin 5-HT 2A receptor, with minimal β-arrestin2 recruitment, and likewise has been associated with little tolerance to its hallucinogenic effects. [168] [142] As DMT has been shown to have slightly better efficacy (EC 50) at human serotonin 2C receptor than at the 2A ...

  8. Psychoplastogen - Wikipedia

    en.wikipedia.org/wiki/Psychoplastogen

    To date studies have explored the utility of psilocybin in a variety of diseases, including TRD, [14] [15] smoking addiction, [16] [17] and anxiety and depression in people with cancer diagnoses. [18] LSD is being tested in phase 2 trials for cluster headaches and anxiety. [19] DMT is being studied for depression. [20]

  9. Psychedelic experience - Wikipedia

    en.wikipedia.org/wiki/Psychedelic_experience

    Psilocybin proved to be an efficient tool when it comes to treating, not only symptoms of depression, but also anxiety along with it. [2] It was also found that these results were long-term upholding the possibility of psilocybin being used as a long-term treatment. [2]

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