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Dermatology. Actinic cheilitis is cheilitis (lip inflammation) caused by long term sunlight exposure. Essentially it is a burn, [2] and a variant of actinic keratosis which occurs on the lip. [5] It is a premalignant condition, [6] as it can develop into squamous cell carcinoma (a type of mouth cancer).
Actinic keratosis. Actinic keratosis (AK), sometimes called solar keratosis or senile keratosis, [1][2] is a pre-cancerous [3] area of thick, scaly, or crusty skin. [4][5] Actinic keratosis is a disorder (-osis) of epidermal keratinocytes that is induced by ultraviolet (UV) light exposure (actin-). [6]
Fluorouracil has been given systemically for anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers (especially head and neck cancers). [12] It has also been given topically (on the skin) for actinic keratoses, skin cancers and Bowen's disease [12] (a type of cutaneous squamous-cell carcinoma), and as eye drops for treatment of ocular surface squamous neoplasia. [13]
51,900 (2015) [9] Cutaneous squamous-cell carcinoma (cSCC), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma. [10] cSCC typically presents as a hard lump with a scaly surface, though it may also present as an ulcer. [1]
Tirbanibulin, sold under the brand name Klisyri, is a medication used for the treatment of actinic keratosis (AK) on the face or scalp. [4][5][6] It functions by inhibiting both tubulin polymerization and Src kinase signaling. [7] It is potentially effective in impeding the development of squamous cell carcinoma in situ.
Photodynamic therapy (PDT) is a form of phototherapy involving light and a photosensitizing chemical substance used in conjunction with molecular oxygen to elicit cell death (phototoxicity). [1] PDT is used in treating acne, wet age-related macular degeneration, psoriasis, and herpes. It is used to treat malignant cancers, [2] including head ...
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