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  2. File:Minimum Inhibitory Concentration.pdf - Wikipedia

    en.wikipedia.org/wiki/File:Minimum_Inhibitory...

    It is used to measure the Minimum Inhibitory Concentration [MIC] of an antimicrobial agent, which is the lowest concentration of antimicrobial agent that will inhibit the growth of microbes. The turbidity of the tubes indicates the amount of microbe growth, with the least turbid, or clear, tubes (tubes 6 and 7) correlating with the absence of ...

  3. IC50 - Wikipedia

    en.wikipedia.org/wiki/IC50

    Half maximal inhibitory concentration (IC 50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function. IC 50 is a quantitative measure that indicates how much of a particular inhibitory substance (e.g. drug) is needed to inhibit, in vitro , a given biological process or biological component by 50% ...

  4. Antibiotic sensitivity testing - Wikipedia

    en.wikipedia.org/wiki/Antibiotic_sensitivity_testing

    Breakpoints for the same organism and antibiotic may differ based on the site of infection: [29] for example, the CLSI generally defines Streptococcus pneumoniae as sensitive to intravenous penicillin if MICs are ≤0.06 μg/ml, intermediate if MICs are 0.12 to 1 μg/ml, and resistant if MICs are ≥2 μg/ml, but for cases of meningitis, the ...

  5. Minimum inhibitory concentration - Wikipedia

    en.wikipedia.org/wiki/Minimum_inhibitory...

    In microbiology, the minimum inhibitory concentration (MIC) is the lowest concentration of a chemical, usually a drug, which prevents visible in vitro growth of bacteria or fungi. [ 1 ] [ 2 ] MIC testing is performed in both diagnostic [ 1 ] [ 2 ] and drug discovery laboratories.

  6. European Committee on Antimicrobial Susceptibility Testing

    en.wikipedia.org/wiki/European_Committee_on...

    European Committee on Antimicrobial Susceptibility Testing (EUCAST) is a scientific committee for defining guidelines to interpret antimicrobial resistance. [1] It was formed in 1997 and is jointly organized by ESCMID , ECDC and other European laboratories.

  7. Disk diffusion test - Wikipedia

    en.wikipedia.org/wiki/Disk_diffusion_test

    This is the zone of inhibition. In general, larger zones of inhibition correlate with lower minimum inhibitory concentrations (MICs) of antibiotic or extract for that bacterial strain. [1] An exception to this is when molecules of the antibiotic or extract are large or hydrophobic because these diffuse through the agar slowly. [6]

  8. EC50 - Wikipedia

    en.wikipedia.org/wiki/EC50

    The EC 10 and EC 90 concentrations to induce 10% and 90% maximal responses are defined similarly. There is a wide range of EC 50 values of drugs; they are typically anywhere from nM to mM. Hence, it is often more practical to refer to the logarithmically transformed p EC 50 values instead of EC 50 , where

  9. Wortmannin - Wikipedia

    en.wikipedia.org/wiki/Wortmannin

    Wortmannin, a steroid metabolite of the fungi Penicillium funiculosum, Talaromyces wortmannii, is a non-specific, covalent inhibitor of phosphoinositide 3-kinases (PI3Ks). ). It has an in vitro inhibitory concentration (IC 50) of around 5 nM, making it a more potent inhibitor than LY294002, another commonly used PI3K inhib