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Inactivated flu vaccines cannot cause influenza and are regarded as safe during pregnancy. [96] While side effects of the flu vaccine may occur, they are usually minor, including soreness, redness, swelling around the point of injection, headache, fever, nausea, or fatigue. [150]
[49] [50] [51] However, the use of the preparation has been described as "imprudent" when an influenza strain causes death in healthy adults by cytokine storm leading to primary viral pneumonia. [52] The manufacturer cites a lack of evidence for cytokine-related risks, but labels the product only as an antioxidant and food supplement. [53]
Genes associated with narcolepsy modulate the expression of the specific T cell receptor recognition involved in reaction to these antigens, suggesting H1N1 infection is a cause of narcolepsy in genetically susceptible individuals. T-cells stimulated by Pandemrix were cross-reactive by molecular mimicry with the same part of the hypocretin peptide.
Adults 65 years of age and older can have a weaker immune response to flu vaccines, making them more likely to get sick with the flu or get flu complications even when vaccinated, according to the ...
Anabolism (/ ə ˈ n æ b ə l ɪ z ə m /) is the set of metabolic pathways that construct macromolecules like DNA or RNA from smaller units. [1] [2] These reactions require energy, known also as an endergonic process. [3] Anabolism is the building-up aspect of metabolism, whereas catabolism is the breaking-down aspect. Anabolism is usually ...
The flu can cause a fever, which can increase the odds of sweating. Replacing those fluids is important to keep your body functioning as best as possible while you’re sick, Dr. Russo says.
Viral neuraminidase cleaves terminal sialic acid residues from glycan structures on the surface of the infected cell. This promotes the release of progeny viruses and the spread of the virus from the host cell to uninfected surrounding cells. Neuraminidase also cleaves sialic acid residues from viral proteins, preventing aggregation of viruses.
In November 2013, the U.S. Food and Drug Administration (FDA) approved an experimental H5N1 bird flu vaccine to be held in stockpiles. [22] [23] In a clinical trial including 3,400 adults, 91% of people age 18–64 and 74% of people age 65 or older formed an immune response sufficient to provide protection. Reported adverse effects were ...
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